Prevention of multiple sclerosis: A realistic goal?

被引：0
作者：
Vukusic, S. [1 ,2 ,3 ,4 ,5 ,6 ]
机构：
[1] Hosp Civils Lyon, Hop Neurol Pierre Wertheimer, Serv Neurol A, F-69677 Lyon, France
[2] Hosp Civils Lyon, Hop Neurol Pierre Wertheimer, Fdn Eugene Dev EDMUS Sclerose Plaques, F-69677 Lyon, France
[3] Equipe Neurooncol & Neuroinflammat, Ctr Neurosci Lyon, Inserm U1028, F-69003 Lyon, France
[4] Equipe Neurooncol & Neuroinflammat, Ctr Neurosci Lyon, CNRS UMR 5292, F-69003 Lyon, France
[5] Univ Lyon, F-69003 Lyon, France
[6] Univ Lyon 1, F-69003 Lyon, France
来源：
REVUE NEUROLOGIQUE | 2012年 / 168卷 / 11期
关键词：
Multiple sclerosis; Genes; Environment; Prevention; Vitamin D; RADIOLOGICALLY ISOLATED SYNDROME; CLINICALLY ISOLATED SYNDROMES; ENVIRONMENTAL RISK-FACTORS; VITAMIN-D INSUFFICIENCY; FOLLOW-UP; DIAGNOSTIC-CRITERIA; OPTIC NEURITIS; PREDICT CONVERSION; MRI CRITERIA; SEX-RATIO;
D O I：
10.1016/j.neurol.2012.07.008
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Multiple sclerosis (MS) is the most frequent source of chronic neurological disability in Western countries, and its incidence and prevalence are increasing. However, it is possible to determine its prodromal phase and the radiological, biological and immunological endophenotypes that are present before the clinical onset of the disease, despite remaining unseen with the naked eye. In this context, greater knowledge of the aetiological factors, both genetic and environmental, may lead the way towards primary prevention strategies for MS in the near future. (C) 2012 Published by Elsevier Masson SAS.
引用
收藏
页码：836 / 845
页数：10
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