Patterns of management and surveillance imaging amongst medical oncologists in Australia for stage I testicular cancer

被引:13
作者
Grimison, Peter [1 ,2 ,3 ]
Houghton, Baerin [1 ,4 ]
Chatfield, Mark [1 ,4 ]
Toner, Guy C. [1 ,6 ,7 ]
Davis, Ian D. [1 ,8 ]
Martin, Jarad [1 ]
Hovey, Elizabeth [1 ,5 ]
Stockler, Martin R. [1 ,2 ,3 ,4 ]
机构
[1] Canc Trials Grp Ltd, ANZUP, Sydney, NSW, Australia
[2] Sydney Canc Ctr, Sydney, NSW, Australia
[3] Univ Sydney, Sydney, NSW 2006, Australia
[4] Univ Sydney, NHMRC Clin Trials Ctr, Sydney, NSW 2006, Australia
[5] Prince Wales Hosp, Randwick, NSW 2031, Australia
[6] Peter MacCallum Canc Inst, Melbourne, Vic 3000, Australia
[7] Univ Melbourne, Melbourne, Vic, Australia
[8] Austin Hlth, Ludwig Inst Canc Res, Joint Ludwig Austin Oncol Unit, Melbourne, Vic, Australia
基金
英国医学研究理事会;
关键词
adjuvant chemotherapy; local neoplasm recurrence; epidemiology; pathology; adjuvant radiotherapy; testicular neoplasms; mortality; watchful waiting; standards; GERM-CELL-CANCER; CLINICAL-PRACTICE GUIDELINES; ADJUVANT TREATMENT; COMPUTED-TOMOGRAPHY; FOLLOW-UP; RANDOMIZED-TRIAL; TESTIS CANCER; SEMINOMA; RADIATION; DIAGNOSIS;
D O I
10.1111/bju.12221
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Objective To determine the patterns of management and surveillance imaging amongst medical oncologists in Australia for stage I testicular cancer during 2010. Methods We conducted a survey comprising 14 questions about the management strategy and surveillance imaging for all patients with stage I testicular cancer treated over the previous 12 months. Results A total of 52 medical oncologists documented the management for an estimated 470 patients. For seminoma, management was in the form of surveillance in 33%, radiotherapy in 5% and adjuvant carboplatin in 62% of patients. For non-seminoma, management was surveillance in 73%, adjuvant chemotherapy in 23% and retroperitoneal lymph node dissection in 4% of patients. The frequency of surveillance imaging was highly variable, and 10 computed tomography (CT) scans were used by 38% of clinicians for seminoma and 46% of clinicians for non-seminoma. Conclusion We found considerable variation in management patterns. The infrequent use of surveillance and frequent use of carboplatin for seminoma differs from international guidelines. Radiation exposure from CT imaging should be reduced through standardized follow-up protocols, and possibly by alternate imaging methods if validated in appropriate studies.
引用
收藏
页码:E35 / E43
页数:9
相关论文
共 49 条
[1]  
Albers P, 2011, GUIDELINES TESTICULA
[2]   Randomized phase III trial comparing retroperitoneal lymph node dissection with one course of bleomycin and etoposide plus cisplatin chemotherapy in the adjuvant treatment of clinical stage I nonseminomatous testicular germ cell tumors: AUO trial AH 01/94 by the German testicular cancer study group [J].
Albers, Peter ;
Siener, Roswitha ;
Krege, Susanne ;
Schmelz, Hans-Uwe ;
Dieckmann, Klaus-Peter ;
Heidenreich, Axel ;
Kwasny, Peter ;
Pechoel, Maik ;
Lehmann, Jan ;
Kliesch, Sabine ;
Koehrmann, Kai-Uwe ;
Fimmers, Rolf ;
Weissbach, Lothar ;
Loy, Volker ;
Wittekind, Christian ;
Hartmann, Michael .
JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (18) :2966-2972
[3]  
[Anonymous], 2012, NCCN Clinical Practice Guidelines in Oncology: Breast Cancer
[4]   Barriers to the Implementation of Surveillance for Stage I Testicular Seminoma [J].
Arvold, Nils D. ;
Catalano, Paul J. ;
Sweeney, Christopher J. ;
Hoffman, Karen E. ;
Nguyen, Paul L. ;
Balboni, Tracy A. ;
Fossa, Sophie D. ;
Travis, Lois B. ;
Beard, Clair J. .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2012, 84 (02) :383-389
[5]   Uptake of oncology multidisciplinary meeting recommendations [J].
Au-Yeung, George H. ;
Aly, Ahmad ;
Bui, Andrew ;
Vermeltfoort, Carmel M. ;
Davis, Ian D. .
MEDICAL JOURNAL OF AUSTRALIA, 2012, 196 (01) :36-37
[6]   Risk of cancer from diagnostic X-rays:: estimates for the UK and 14 other countries [J].
Berrington de González, A ;
Darby, S .
LANCET, 2004, 363 (9406) :345-351
[7]   Current concepts - Computed tomography - An increasing source of radiation exposure [J].
Brenner, David J. ;
Hall, Eric J. .
NEW ENGLAND JOURNAL OF MEDICINE, 2007, 357 (22) :2277-2284
[8]   Interdisciplinary Evidence-Based Recommendations for the Follow-Up of Testicular Germ Cell Cancer Patients [J].
Cathomas, Richard ;
Hartmann, Michael ;
Krege, Susanne ;
Souchon, Rainer ;
Lorch, Anja ;
Mayer, Frank ;
De Santis, Maria ;
Gillessen, Silke .
ONKOLOGIE, 2011, 34 (1-2) :59-64
[9]   Management of Stage I Seminomatous Testicular Cancer: a Systematic Review [J].
Chung, P. ;
Mayhew, L. A. ;
Warde, P. ;
Winquist, E. ;
Lukka, H. .
CLINICAL ONCOLOGY, 2010, 22 (01) :6-16
[10]   Stage I Seminoma: Adjuvant Treatment is Effective but is it Necessary? [J].
Chung, Peter ;
Warde, Padraig .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2011, 103 (03)