Antimicrobial action of propolis and some of its components: the effects on growth, membrane potential and motility of bacteria

被引:0
作者
Mirzoeva, OK [1 ]
Grishanin, RN [1 ]
Calder, PC [1 ]
机构
[1] UNIV OXFORD,DEPT BIOCHEM,OXFORD OX1 3QU,ENGLAND
关键词
propolis; bactericidal effect; membrane potential;
D O I
暂无
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The effect of the natural bee product propolis on the physiology of microorganisms was investigated using B. subtilis, E. coli and R. sphaeroides. An ethanolic extract of propolis had a bactericidal effect caused by the presence of very active, but labile, ingredients. The exact bactericidal effect of propolis was species dependent: it was effective against gram-positive and some gram-negative bacteria. Propolis and some of its cinnamic and flavonoid components were found to uncouple the energy tranducing cytoplasmic membrane and to inhibit bacterial motility. These effects on the bioenergetic status of the membrane may contribute to the antimicrobial action of propolis and its observed synergism with selected antibiotics.
引用
收藏
页码:239 / 246
页数:8
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