Junction probes - Sequence specific detection of nucleic acids via Template Enhanced Hybridization Processes

被引：81

作者：

Nakayama, Shizuka ^{[1
]}

Yan, Lei ^{[1
]}

Sintim, Herman O. ^{[1
]}

机构：

[1] Univ Maryland, Dept Chem & Biochem, College Pk, MD 20742 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2008年 / 130卷 / 38期

关键词：

D O I：

10.1021/ja803146f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Junction probe nucleic acid detection technology allows the amplified sensing of analytes at isothermal conditions. The addition of a second dimension to detection probes permits the use of cheap commercially available DNA processing enzymes such as restriction endonucleases to detect single nucleotide polymorphisms, SNPs.

引用

页码：12560 / +

页数：3

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