The Impact of Genomics on Public Health Practice: The Case for Change

被引:27
作者
Zimmern, R. L. [1 ]
Khoury, M. J. [2 ,3 ]
机构
[1] Fdn Genom & Populat Hlth, Cambridge CB1 8RN, England
[2] NCI, Div Canc Control & Populat Sci, Bethesda, MD 20892 USA
[3] Ctr Dis Control & Prevent, Off Publ Hlth Genom, Atlanta, GA USA
关键词
Genetics; Genomics; Health policy; Personalised medicine; Public health; Translation;
D O I
10.1159/000334840
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Public health practice will not be able in the 21st century to ignore the impact of genomics, cell and molecular biology. It will need to take into consideration issues that include, among others: the complementary nature of social and biological models of disease, genetic exceptionalism, the readiness of public and patient to respond to genomic information, the relationship between individuals and populations, and concepts of population stratification. Health systems will need to adapt their practice and organisation to include new sequencing technologies, bioinformatic expertise and proper evaluation of genetic and molecular tests. Links with the commercial sector will increase in importance. The impact on developing countries cannot be ignored and will require special attention. Copyright (c) 2012 S. Karger AG, Basel
引用
收藏
页码:118 / 124
页数:7
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