Preparation and Characterization of Magnetic Mesoporous Bioactive Glass/Carbon Composite Scaffolds

被引：19

作者：

Zhu, Min ^{[1
]}

Zhang, Jianhua ^{[1
]}

Zhou, Yinghong ^{[2
]}

Liu, Yunfei ^{[3
]}

He, Xing ^{[1
]}

Tao, Cuilian ^{[1
]}

Zhu, Yufang ^{[1
]}

机构：

[1] Univ Shanghai Sci & Technol, Sch Mat Sci & Engn, Shanghai 200093, Peoples R China

[2] Queensland Univ Technol, Inst Hlth & Biomed Innovat, Brisbane, Qld 4059, Australia

[3] Nanjing Univ Technol, Coll Mat Sci & Engn, Nanjing 210009, Jiangsu, Peoples R China

来源：

JOURNAL OF CHEMISTRY | 2013年 / 2013卷

基金：

中国国家自然科学基金;

关键词：

IN-VITRO BIOACTIVITY; GLASS SCAFFOLDS; DRUG-DELIVERY; SUSTAINED-RELEASE; FOAM SCAFFOLDS; SILICA SPHERES; HYPERTHERMIA; ZINC; DIFFERENTIATION; REGENERATION;

D O I：

10.1155/2013/893479

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The magnetic Fe-MBG/C composite scaffolds with enhanced mechanical strength and multifunctionality have been successfully prepared. The study showed that the Fe-MBG/C composite scaffolds with the porosity of ca. 80% had interconnected macropores (200-500 mu m) and mesopores (3.7-4.4 nm) and significantly enhanced the compressive strength compared to the pure MBG scaffolds. Importantly, the Fe-MBG/C composite scaffolds exhibited good bioactivity and sustained drug release property. At the same time, the Fe-MBG/C composite scaffolds could generate heat to raise the temperature of surrounding environment in an alternating magnetic field due to their superparamagnetic behavior. Therefore, the magnetic Fe-MBG/C composite scaffolds could form a multifunctional platform with bone regeneration, magnetic hyperthermia, and local drug delivery and have more potential for use in the regeneration of the critical-sized bone defects caused by bone tumors.

引用

页数：11

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