Projection X-Space Magnetic Particle Imaging

被引:127
作者
Goodwill, Patrick W. [1 ]
Konkle, Justin J. [1 ]
Zheng, Bo
Saritas, Emine U. [1 ]
Conolly, Steven M. [1 ]
机构
[1] Univ Calif Berkeley, Dept Bioengn, Berkeley, CA 94720 USA
关键词
Angiography biomedical imaging; magnetic particle imaging (MPI); magnetic particles; RESOLUTION; SENSITIVITY; MR;
D O I
10.1109/TMI.2012.2185247
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
Projection magnetic particle imaging (MPI) can improve imaging speed by over 100-fold over traditional 3-D MPI. In this work, we derive the 2-D x-space signal equation, 2-D image equation, and introduce the concept of signal fading and resolution loss for a projection MPI imager. We then describe the design and construction of an x-space projection MPI scanner with a field gradient of 2.35 T/m across a 10 cm magnet free bore. The system has an expected resolution of 3.5 x 8.0 mm using Resovist tracer, and an experimental resolution of 3.8 x 8.4 mm resolution. The system images 2.5 cm x 5.0 cm partial field-of views (FOVs) at 10 frames/s, and acquires a full field-of-view of 10 cm 5.0 cm in 4 s. We conclude by imaging a resolution phantom, a complex "Cal" phantom, mice injected with Resovist tracer, and experimentally confirm the theoretically predicted x-space spatial resolution.
引用
收藏
页码:1076 / 1085
页数:10
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