Projection X-Space Magnetic Particle Imaging

被引：131

作者：

Goodwill, Patrick W. ^{[1
]}

Konkle, Justin J. ^{[1
]}

Zheng, Bo

Saritas, Emine U. ^{[1
]}

Conolly, Steven M. ^{[1
]}

机构：

[1] Univ Calif Berkeley, Dept Bioengn, Berkeley, CA 94720 USA

来源：

IEEE TRANSACTIONS ON MEDICAL IMAGING | 2012年 / 31卷 / 05期

关键词：

Angiography biomedical imaging; magnetic particle imaging (MPI); magnetic particles; RESOLUTION; SENSITIVITY; MR;

D O I：

10.1109/TMI.2012.2185247

中图分类号：

TP39 [计算机的应用];

学科分类号：

081203 ; 0835 ;

摘要：

Projection magnetic particle imaging (MPI) can improve imaging speed by over 100-fold over traditional 3-D MPI. In this work, we derive the 2-D x-space signal equation, 2-D image equation, and introduce the concept of signal fading and resolution loss for a projection MPI imager. We then describe the design and construction of an x-space projection MPI scanner with a field gradient of 2.35 T/m across a 10 cm magnet free bore. The system has an expected resolution of 3.5 x 8.0 mm using Resovist tracer, and an experimental resolution of 3.8 x 8.4 mm resolution. The system images 2.5 cm x 5.0 cm partial field-of views (FOVs) at 10 frames/s, and acquires a full field-of-view of 10 cm 5.0 cm in 4 s. We conclude by imaging a resolution phantom, a complex "Cal" phantom, mice injected with Resovist tracer, and experimentally confirm the theoretically predicted x-space spatial resolution.

引用

页码：1076 / 1085

页数：10

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