Limit of detection estimator for second-order bilinear calibration

被引：78

作者：

Boqué, R

Ferré, J

Faber, NM

Rius, FX

机构：

[1] Univ Rovira & Virgili, Inst Adv Studies, Dept Analyt & Organ Chem, E-43005 Tarragona, Spain

[2] ATO, Dept Prod & Control Syst, NL-6700 AA Wageningen, Netherlands

来源：

ANALYTICA CHIMICA ACTA | 2002年 / 451卷 / 02期

关键词：

limit of detection; second-order bilinear calibration; GRAM; prediction variance; prediction bias;

D O I：

10.1016/S0003-2670(01)01395-2

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A new approach is developed for estimating the limit of detection in second-order bilinear calibration with the generalized rank annihilation method (GRAM). The proposed estimator is based on recently derived expressions for prediction variance and bias. It follows the latest IUPAC recommendations in the sense that it concisely accounts for the probabilities of committing both types I and II errors, i.e. false positive and false negative declarations, respectively. The estimator has been extensively validated with simulated data, yielding promising results. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：313 / 321

页数：9