Exploring ART Intake Scenes in a Human Rights-Based Intervention to Improve Adherence: A Randomized Controlled Trial

被引：13

作者：

Basso, Caritas Relva ^{[1
,2
]}

Santa Helena, Ernani Tiaraju ^{[2
,3
]}

Magalhaes Caraciolo, Joselita Maria ^{[1
,2
]}

Paiva, Vera ^{[4
]}

Battistela Nemes, Maria Ines ^{[2
]}

机构：

[1] Reference & Training Ctr Sexually Transmitted Inf, BR-4112000 Sao Paulo, Brazil

[2] Univ Sao Paulo, Fac Med, Dept Prevent Med, Sao Paulo, Brazil

[3] Univ Reg Blumenau, Blumenau, SC, Brazil

[4] Univ Sao Paulo, Dept Social Psychol, Inst Psychol, Sao Paulo, Brazil

来源：

AIDS AND BEHAVIOR | 2013年 / 17卷 / 01期

基金：

巴西圣保罗研究基金会;

关键词：

Antiretroviral therapy; HAART; HIV/AIDS; Adherence intervention; Psychosocial intervention; Social constructionism; Human rights; ANTIRETROVIRAL THERAPY ADHERENCE; HUMAN-IMMUNODEFICIENCY-VIRUS; PATIENT ADHERENCE; BEHAVIORAL INTERVENTION; MEDICATION ADHERENCE; COST-EFFECTIVENESS; INHIBITOR THERAPY; DRUG-RESISTANCE; HIV PATIENTS; VIRAL LOAD;

D O I：

10.1007/s10461-012-0175-4

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

To assess the effectiveness of a psychosocial individual intervention to improve adherence to ART in a Brazilian reference-center, consenting PLHIV with viral load > 50 copies/ml were selected. After 4 weeks of MEMS cap use, participants were randomized into an intervention group (IG) (n = 64) or control group (CG) (n = 57). CG received usual care only. The IG participated in a human rights-based intervention approach entailing four dialogical meetings focused on medication intake scenes. Comparison between IG and CG revealed no statistically significant difference in adherence measured at weeks 8, 12, 16, 20 and 24. Viral load (VL) decreased in both groups (p < 0.0001) with no significant difference between study groups. The lower number of eligible patients than expected underpowered the study. Ongoing qualitative analysis should provide deeper understanding of the trial results. NIH Clinical Trials: NCTOO716040.

引用

页码：181 / 192

页数：12

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