Microwave-assisted Friedel-Crafts acylation of indole with acetic anhydride over tungstophosphoric acid modified Hβ zeolite

被引：23

作者：

Bai, Guoyi ^{[1
]}

Li, Tianyu ^{[1
]}

Yang, Yonghui ^{[1
]}

Zhang, Huanhuan ^{[1
]}

Lan, Xingwang ^{[1
]}

Li, Fei ^{[1
]}

Han, Jie ^{[1
]}

Ma, Zheng ^{[1
]}

Chen, Qingzhi ^{[1
]}

Chen, Guofeng ^{[1
]}

机构：

[1] Hebei Univ, Key Lab Chem Biol Hebei Prov, Coll Chem & Environm Sci, Baoding 071002, Hebei, Peoples R China

来源：

CATALYSIS COMMUNICATIONS | 2012年 / 29卷

基金：

中国国家自然科学基金;

关键词：

Microwave; Friedel-Crafts acylation; Zeolite; Acid modified; 3-Acetylindole; CATALYST; ACETYLATION; EFFICIENT; ANISOLE;

D O I：

10.1016/j.catcom.2012.09.028

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Friedel-Crafts acylation of indole with acetic anhydride has been carried out over zeolites under microwave and conventional heating, respectively. A tungstophosphoric acid modified H beta (PW-H beta) zeolite showed better catalytic performance than parent H beta zeolite due to its higher amount of strongly acidic sites and lower amount of Lewis acid sites, confirmed from NH3 temperature-programmed desorption (NH3-TPD) and Fourier Transform Infrared Spectrometer after adsorption of pyridine (Py-IR). Particularly, microwave radiation was found to make this transformation not only more efficient but also selective to 3-acetylindole compared with conventional heating. Furthermore, PW-H beta has shown good stability in this reaction. (C) 2012 Elsevier B.V. All rights reserved.

引用

页码：114 / 117

页数：4

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