A graphene-based multifunctional affinity probe for selective capture and sequential identification of different biomarkers from biosamples

被引:35
作者
Cheng, Gong [1 ,4 ]
Wang, Zhi-Gang [1 ,4 ]
Liu, Yan-Lin [1 ,4 ]
Zhang, Ji-Lin [1 ]
Sun, De-Hui [3 ]
Ni, Jia-Zuan [1 ,2 ]
机构
[1] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Rare Earth Resource Utilizat, Changchun 130022, Peoples R China
[2] Shenzhen Univ, Coll Life Sci, Key Lab Marine Bioresources & Ecol, Shenzhen 518060, Peoples R China
[3] Changchun Inst Technol, Changchun 130012, Peoples R China
[4] Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
关键词
TOF-MS ANALYSIS; MAGNETIC SILICA MICROSPHERES; LOW-CONCENTRATION PEPTIDES; LIQUID-CHROMATOGRAPHY; CANCER BIOMARKERS; HIGHLY EFFICIENT; FACILE SYNTHESIS; ENRICHMENT; PHOSPHOPEPTIDES; PROTEOMICS;
D O I
10.1039/c2cc35483g
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A novel multifunctional graphene-based affinity probe has been explored for selective capture of two different types of peptides from the biosamples for sequential detection.
引用
收藏
页码:10240 / 10242
页数:3
相关论文
共 23 条
[1]   Facile synthesis of C8-functionalized magnetic silica microspheres for enrichment of low-concentration peptides for direct MALDI-TOF MS analysis [J].
Chen, Hemei ;
Xu, Xiuqing ;
Yao, Ning ;
Deng, Chunhui ;
Yang, Pengyuan ;
Zhang, Xiangmin .
PROTEOMICS, 2008, 8 (14) :2778-2784
[2]   A Facile Synthesis Approach to C8-Functionalized Magnetic Carbonaceous Polysaccharide Microspheres for the Highly Efficient and Rapid Enrichment of Peptides and Direct MALDI-TOF-MS Analysis [J].
Chen, Hemei ;
Deng, Chunhui ;
Li, Yan ;
Dai, Ying ;
Yang, Penguan ;
Zhang, Xiangmin .
ADVANCED MATERIALS, 2009, 21 (21) :2200-+
[3]   Preparation of C60-functionalized magnetic silica microspheres for the enrichment of low-concentration peptides and proteins for MALDI-TOF MS analysis [J].
Chen, Hemei ;
Qi, Dawei ;
Deng, Chunhui ;
Yang, Penyuan ;
Zhang, Xiangmin .
PROTEOMICS, 2009, 9 (02) :380-387
[4]   Lanthanum silicate coated magnetic microspheres as a promising affinity material for phosphopeptide enrichment and identification [J].
Cheng, Gong ;
Liu, Yan-Lin ;
Zhang, Ji-Lin ;
Sun, De-Hui ;
Ni, Jia-Zuan .
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2012, 404 (03) :763-770
[5]   Monodisperse REPO4 (RE=Yb, Gd, Y) Hollow Microspheres Covered with Nanothorns as Affinity Probes for Selectively Capturing and Labeling Phosphopeptides [J].
Cheng, Gong ;
Zhang, Ji-Lin ;
Liu, Yan-Lin ;
Sun, De-Hui ;
Ni, Jia-Zuan .
CHEMISTRY-A EUROPEAN JOURNAL, 2012, 18 (07) :2014-2020
[6]   Synthesis of novel Fe3O4@SiO2@CeO2 microspheres with mesoporous shell for phosphopeptide capturing and labeling [J].
Cheng, Gong ;
Zhang, Ji-Lin ;
Liu, Yan-Lin ;
Sun, De-Hui ;
Ni, Jia-Zuan .
CHEMICAL COMMUNICATIONS, 2011, 47 (20) :5732-5734
[7]   The biological impact of mass-spectrometry-based proteomics [J].
Cravatt, Benjamin F. ;
Simon, Gabriel M. ;
Yates, John R., III .
NATURE, 2007, 450 (7172) :991-1000
[8]   Phosphorylation and the cell cycle [J].
Doerr, Allison .
NATURE METHODS, 2008, 5 (10) :858-859
[9]   Development of multidimensional liquid chromatography and application in proteomic analysis [J].
Gao, Mingxia ;
Qi, Dawei ;
Zhang, Peng ;
Deng, Chunhui ;
Zhang, Xiangmin .
EXPERT REVIEW OF PROTEOMICS, 2010, 7 (05) :665-678
[10]   Graphene nanosheet: synthesis, molecular engineering, thin film, hybrids, and energy and analytical applications [J].
Guo, Shaojun ;
Dong, Shaojun .
CHEMICAL SOCIETY REVIEWS, 2011, 40 (05) :2644-2672