Metal-free C-N cross-coupling of electrophilic compounds and N-haloimides

被引：11

作者：

Zhang, Luyan ^{[1
]}

Li, Yanru ^{[1
]}

Jin, Long-Yi ^{[3
]}

Liang, Fushun ^{[1
,2
]}

机构：

[1] NE Normal Univ, Dept Chem, Changchun 130024, Peoples R China

[2] NE Normal Univ, Key Lab UV Emitting Mat & Technol, Minist Educ, Changchun 130024, Peoples R China

[3] Yanbian Univ, Fac Chem, Yanbian, Jilin, Peoples R China

来源：

RSC ADVANCES | 2015年 / 5卷 / 80期

基金：

中国国家自然科学基金;

关键词：

HALOGEN-BOND DONORS; ENANTIOSELECTIVE HALOCYCLIZATION; TERTIARY ALKYL; SECONDARY; COMBINATION; ACTIVATION; AMINATION; HALIDES; HETEROARENES; CATALYSTS;

D O I：

10.1039/c5ra13708j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

When DBU is added, the cross-coupling reaction between alkyl halides (halogen = Cl, Br and I) and N-haloimides (halogen = Cl, Br) occurs, resulting in the formation of aminated products. A halogen bond activated nucleophilic substitution mechanism was proposed. The methodology represents an elegant example of applying the halogen bond activation strategy in an organic transformation.

引用

页码：65600 / 65603

页数：4

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