The chiral sequence of a natural peptide inhibitor of HIV-1 integrase elucidated

被引:0
|
作者
De Zotti, Marta [1 ]
Toniolo, Claudio [1 ]
Formaggio, Fernando [1 ]
Kaptein, Bernard [2 ]
Broxterman, Quirinus B. [2 ]
Felock, Peter J. [3 ,4 ]
Hazuda, Daria J. [3 ,4 ]
Singh, Sheo B. [3 ,4 ]
Brueckner, Hans [5 ]
机构
[1] Univ Padua, Dept Chem, CNR, Inst Biomol Chem,Padova Unit, I-35131 Padua, Italy
[2] DSM Pharmaceut Prod, Adv Synth Catalysis & Dev, NL-6160 MD Geleen, Netherlands
[3] Merck Res Labs, Rahway, NJ 07065 USA
[4] Merck Res Labs, West Point, PA 19486 USA
[5] Univ Giessen, Dept Food Sci, D-35392 Giessen, Germany
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:120 / 120
页数:1
相关论文
共 50 条
  • [1] SYNTHESIS AND CONFORMATIONAL ANALYSIS OF A NATURAL PEPTIDE INHIBITOR OF HIV-1 INTEGRASE
    De Zotti, M.
    Damato, F.
    Formaggio, F.
    Crisma, M.
    Schievano, E.
    Mammi, S.
    Kaptein, B.
    Broxterman, Q. B.
    Felock, P. J.
    Hazuda, D. J.
    Singh, S. B.
    Krischbaum, J.
    Brueckner, H.
    Toniolo, C.
    BIOPOLYMERS, 2009, 92 (04) : 351 - 351
  • [2] Complete Absolute Configuration of Integramide A, a Natural, 16-mer Peptide Inhibitor of HIV-1 Integrase, Elucidated by Total Synthesis
    De Zotti, Marta
    Formaggio, Fernando
    Kaptein, Bernard
    Broxterman, Quirinus B.
    Felock, Peter J.
    Hazuda, Daria J.
    Singh, Sheo B.
    Brueckner, Hans
    Toniolo, Claudio
    CHEMBIOCHEM, 2009, 10 (01) : 87 - 90
  • [3] HIV-1 integrase inhibitor
    Lloyd, AW
    DRUG DISCOVERY TODAY, 1996, 1 (04) : 170 - 170
  • [4] Natural polymorphism of the HIV-1 integrase gene and mutations associated with integrase inhibitor resistance
    Lataillade, M.
    Chiarella, J.
    Kozal, M. J.
    ANTIVIRAL THERAPY, 2006, 11 (05) : S28 - S28
  • [5] Natural polymorphism of the HIV-1 integrase gene and mutations associated with integrase inhibitor resistance
    Lataillade, Max
    Chiarella, Jennifer
    Kozal, Michael J.
    ANTIVIRAL THERAPY, 2007, 12 (04) : 563 - 570
  • [6] Peptide fibrils as monomer storage of the covalent HIV-1 integrase inhibitor
    Chandra, Koushik
    Das, Priyadip
    Metanis, Norman
    Friedler, Assaf
    Reches, Meital
    JOURNAL OF PEPTIDE SCIENCE, 2017, 23 (02) : 117 - 121
  • [7] Raltegravir: an integrase inhibitor for HIV-1
    Evering, Teresa H.
    Markowitz, Martin
    EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2008, 17 (03) : 413 - 422
  • [8] Raltegravir, an HIV-1 integrase inhibitor for HIV infection
    Cabrera, Cecilia
    CURRENT OPINION IN INVESTIGATIONAL DRUGS, 2008, 9 (08) : 885 - 898
  • [9] HIV-1 integrase sequence variation and covariation
    Myers, R. E.
    Pillay, D.
    ANTIVIRAL THERAPY, 2007, 12 (05) : S5 - S5
  • [10] HIV-1 integrase sequence variation and covariation
    Myers, R. E.
    Pillay, D.
    ANTIVIRAL THERAPY, 2007, 12 : S5 - S5