18FDG PET and PET-CT for the detection of bone metastases in patients with head and neck cancer. A meta-analysis

被引:12
作者
Yi, Xuelian [1 ]
Fan, Min [2 ]
Liu, Yilin [3 ]
Zhang, Hongting [1 ]
Liu, Shixi [1 ]
机构
[1] Sichuan Univ, West China Hosp, Dept Otorhinolaryngol, Chengdu 610041, Peoples R China
[2] Sichuan Univ, Peoples Hosp Chengdu 7, Dept Otorhinolaryngol, Chengdu 610041, Peoples R China
[3] Sichuan Univ, West China Med Sch, Chengdu 610064, Peoples R China
关键词
(18)FDG PET; bone metastases; head and neck neoplasms; meta-analysis; DISTANT METASTASES; F-18-FDG PET; SPECIFICITY; SENSITIVITY; CARCINOMA; RECURRENT; TUMORS;
D O I
10.1111/1754-9485.12077
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
IntroductionWe performed a meta-analysis to evaluate (18)FDG PET/PET-CT for the detection of bone metastases in patients with head and neck cancer. MethodsWe calculated sensitivities, specificities, likelihood ratios, and constructed summary receiver operating characteristic curves for PET and PET-CT, respectively. We also compared the performance of PET/PET-CT with that of bone scintigraphy by analysing studies that had also used bone scintigraphy on the same patients. ResultsAcross 9 PET studies (1621 patients) and 10 PET-CT studies (1291 patients), sensitivity and specificity of PET were 0.81 and 0.99, and of PET-CT were 0.89 and 0.99, respectively. In 5 comparative studies (1184 patients), sensitivity and specificity of PET/PET-CT were 0.85 and 0.98, and of bone scintigraphy were 0.55 and 0.98, respectively. Conclusions(18)FDG PET and PET-CT have high sensitivity and accuracy for the detection of bone metastasis in patients with head and neck cancer.
引用
收藏
页码:674 / 679
页数:6
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