Introduction to Autoinflammatory Syndromes and Diseases

被引:15
作者
Abramovits, William [1 ,2 ,3 ,4 ,5 ]
Oquendo, Marcial [5 ]
机构
[1] Baylor Univ, Med Ctr, Dept Med, Dallas, TX 75246 USA
[2] Texas A&M Med Sch, Dallas, TX 75246 USA
[3] Univ Texas Southwestern Med Sch, Dept Dermatol, Dallas, TX 75235 USA
[4] Univ Texas Southwestern Med Sch, Dept Family Practice, Dallas, TX 75235 USA
[5] Dermatol Treatment & Res Ctr, Dallas, TX 75230 USA
关键词
Autoinflammation; Inflammasome; Interleukins; Recurrent fever; Familial Mediterranean fever; PYOGENIC BACTERIAL-INFECTIONS; REGULATORY T-CELLS; NF-KAPPA-B; RECEPTOR ANTAGONIST; PERIODIC FEVER; RHEUMATOID-ARTHRITIS; THERAPEUTIC APPROACH; SCHNITZLER-SYNDROME; JOINT CONTRACTURES; PROTEASOME SUBUNIT;
D O I
10.1016/j.det.2013.04.010
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Autoinflammatory syndromes and diseases are a group of disorders of innate immunity. This group has grown rapidly in recent years as a result of research advancements in molecular biology and genetics. These diseases often present with skin manifestations and the dermatologist may not recognize the constellation of symptoms and medical history as a systemic inflammatory disease. Dermatologists would benefit from a deeper understanding of these diseases and the new treatments available for them.
引用
收藏
页码:363 / +
页数:24
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