Whole body exposure to 2.4 GHz WIFI signals: Effects on cognitive impairment in adult triple transgenic mouse models of Alzheimer's disease (3xTg-AD)

被引：46
作者：
Banaceur, Sana [1 ]
Banasr, Sihem [1 ]
Sakly, Mohsen [1 ]
Abdelmelek, Hafedh [1 ]
机构：
[1] Fac Sci Bizerte, Lab Physiol Integree, Jarzouna 7021, Tunisia
来源：
BEHAVIOURAL BRAIN RESEARCH | 2013年 / 240卷
关键词：
Alzheimer's disease; Electromagnetic fields; Memory; Transgenic mice (3xTg-AD); STATIC MAGNETIC-FIELD; HEAD-ONLY EXPOSURE; ELECTROMAGNETIC-FIELDS; SPATIAL MEMORY; MICROWAVE-RADIATION; MAZE PERFORMANCE; LEARNING TASKS; MOBILE PHONES; RATS; BRAIN;
D O I：
10.1016/j.bbr.2012.11.021
中图分类号：
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号：
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要：
The present investigation aimed at evaluating the effects of long-term exposure to WIFI type radiofrequency (RF) signals (2.40 GHz), two hours per day during one month at a Specific Absorption Rate (SAR) of 1.60 W/kg. The effects of RF exposure were studied on wildtype mice and triple transgenic mice (3xTg-AD) destined to develop Alzheimer's-like cognitive impairment. Mice were divided into four groups: two sham groups (WT, TG; n = 7) and two exposed groups (WTS, TGS; n = 7). The cognitive interference task used in this study was designed from an analogous human cognitive interference task including the Flex field activity system test, the two-compartment box test and the Barnes maze test. Our data demonstrate for the first time that RF improves cognitive behavior of 3xTg-AD mice. We conclude that RF exposure may represent an effective memory-enhancing approach in Alzheimer's disease. (C) 2012 Elsevier B.V. All rights reserved.
引用
收藏
页码：197 / 201
页数：5
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