Disparate roles of chiral ligands and molecularly imprinted cavities in asymmetric catalysis and chiral poisoning

被引：33

作者：

Koh, JH ^{[1
]}

Larsen, AO ^{[1
]}

White, PS ^{[1
]}

Gagné, MR ^{[1
]}

机构：

[1] Univ N Carolina, Dept Chem, Chapel Hill, NC 27599 USA

来源：

ORGANOMETALLICS | 2002年 / 21卷 / 01期

关键词：

D O I：

10.1021/om010944c

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The activation of molecularly imprinted metal complexes generates Lewis acid catalysts for the ene reaction, each of which contains a chiral diphosphine ligand and a chiral BINOL-shaped cavity. Poisoning experiments with (R)- and (S)-BINAM indicate that while the chiral cavity can differentiate the chiral poisons, it is the chiral diphosphine ligand which controls the enantioselectivity of the ene product.

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页码：7 / 9

页数：3

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