MICROWAVE-ASSISTED SYNTHESIS AND EVALUATION OF ANTIBACTERIAL ACTIVITY OF 2,2′-(NAPHTHALENE-2,7-DIYLBIS(OXY))BIS(N′-SUBSTITUTED ACETOHYDRAZIDE) DERIVATIVES

被引：7
作者：
Venkatesan, K. [1 ]
Satyanarayana, V. S. V. [1 ]
Sivakumar, A. [1 ]
机构：
[1] VIT Univ, Sch Adv Sci, Div Chem, Vellore 632014, Tamil Nadu, India
来源：
BULLETIN OF THE CHEMICAL SOCIETY OF ETHIOPIA | 2012年 / 26卷 / 02期
关键词：
2,2 '-(Naphthalene-2,7-diylbis(oxy))diacetohydrazide; Schiff base; Microwave irradiation; Spectral characterization; Antibacterial activity; ISATIN DERIVATIVES; ANTITUMOR-ACTIVITY; ORGANIC-SYNTHESIS; MANNICH-BASES; SCHIFF-BASES; ANTIFUNGAL; INHIBITORS; ANALOGS; AGENTS;
D O I：
10.4314/bcse.v26i2.9
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A series of Schiff base of 2,2'-(naphthalene-2,7-diylbis(oxy))bis(N'-substituted acetohydrazide) (4a-m) derivatives has been synthesized by the acid catalyzed condensation of aryl/hetero aromatic aldehydes with 2,2'-(naphthalene-2,7-diylbis(oxy))diacetohydrazide (3) under microwave irradiation and conventional method for comparison. The structures of all the newly synthesized compounds have been characterized by IR, H-1 NMR, C-13 NMR and Mass spectra. All the synthesized compounds have been screened for their in vitro antibacterial activity.
引用
收藏
页码：257 / 265
页数：9
相关论文
共 25 条
[21]  
Satyanarayana VSV, 2011, LETT DRUG DES DISCOV, V8, P276
[22]  
Satyanarayana VSV, 2011, ASIAN J CHEM, V23, P1212
[23]   Synthesis and antibacterial screening of hydrazones, Schiff and Mannich bases of isatin derivatives [J].
Sridhar, SK ;
Saravanan, M ;
Ramesh, A .
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2001, 36 (7-8) :615-625
[24]  
Valentina P., 2009, J. Pharm. Sci. Res, V1, P74
[25]   Synthesis of 3-acetoxyazetidin-2-ones and 3-hydroxyazetidin-2-ones with antifungal and antibacterial activity [J].
Walsh, OM ;
Meegan, MJ ;
Prendergast, RM ;
AlNakib, T .
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 1996, 31 (12) :989-1000
123