MICROWAVE-ASSISTED SYNTHESIS AND EVALUATION OF ANTIBACTERIAL ACTIVITY OF 2,2′-(NAPHTHALENE-2,7-DIYLBIS(OXY))BIS(N′-SUBSTITUTED ACETOHYDRAZIDE) DERIVATIVES

被引：7

作者：

Venkatesan, K. ^{[1
]}

Satyanarayana, V. S. V. ^{[1
]}

Sivakumar, A. ^{[1
]}

机构：

[1] VIT Univ, Sch Adv Sci, Div Chem, Vellore 632014, Tamil Nadu, India

来源：

BULLETIN OF THE CHEMICAL SOCIETY OF ETHIOPIA | 2012年 / 26卷 / 02期

关键词：

2,2 '-(Naphthalene-2,7-diylbis(oxy))diacetohydrazide; Schiff base; Microwave irradiation; Spectral characterization; Antibacterial activity; ISATIN DERIVATIVES; ANTITUMOR-ACTIVITY; ORGANIC-SYNTHESIS; MANNICH-BASES; SCHIFF-BASES; ANTIFUNGAL; INHIBITORS; ANALOGS; AGENTS;

D O I：

10.4314/bcse.v26i2.9

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A series of Schiff base of 2,2'-(naphthalene-2,7-diylbis(oxy))bis(N'-substituted acetohydrazide) (4a-m) derivatives has been synthesized by the acid catalyzed condensation of aryl/hetero aromatic aldehydes with 2,2'-(naphthalene-2,7-diylbis(oxy))diacetohydrazide (3) under microwave irradiation and conventional method for comparison. The structures of all the newly synthesized compounds have been characterized by IR, H-1 NMR, C-13 NMR and Mass spectra. All the synthesized compounds have been screened for their in vitro antibacterial activity.

引用

页码：257 / 265

页数：9

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