A resistosome-activated 'death switch'

被引:16
作者
Adachi, Hiroaki [1 ]
Kamoun, Sophien [1 ]
Maqbool, Abbas [1 ]
机构
[1] Univ East Anglia, Sainsbury Lab, Norwich Res Pk, Norwich, Norfolk, England
基金
英国生物技术与生命科学研究理事会;
关键词
D O I
10.1038/s41477-019-0425-9
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Pathogen perception triggers a monomeric nucleotide-binding leucine-rich plant immune receptor to form a pentameric wheel-like complex termed a resistosome, with the N-terminal alpha helices forming a funnel-shaped structure that may perturb plasma membrane integrity to cause hypersensitive cell death.
引用
收藏
页码:457 / 458
页数:2
相关论文
共 15 条
  • [1] Adachi H., 2019, ZENODO, DOI [10.5281/zenodo.2560083, DOI 10.5281/ZENODO.2560083]
  • [2] Convergence of cell-surface and intracellular immune receptor signalling
    Adachi, Hiroaki
    Tsuda, Kenichi
    [J]. NEW PHYTOLOGIST, 2019, 221 (04) : 1676 - 1678
  • [3] Animal NLRs provide structural insights into plant NLR function
    Bentham, Adam
    Burdett, Hayden
    Anderson, Peter A.
    Williams, Simon J.
    Kobe, Bostjan
    [J]. ANNALS OF BOTANY, 2017, 119 (05) : 689 - 702
  • [4] Salicylic Acid and Jasmonic Acid Pathways are Activated in Spatially Different Domains Around the Infection Site During Effector-Triggered Immunity in Arabidopsis thaliana
    Betsuyaku, Shigeyuki
    Katou, Shinpei
    Takebayashi, Yumiko
    Sakakibara, Hitoshi
    Nomura, Nobuhiko
    Fukuda, Hiroo
    [J]. PLANT AND CELL PHYSIOLOGY, 2018, 59 (01) : 8 - 16
  • [5] Prion-like Polymerization Underlies Signal Transduction in Antiviral Immune Defense and Inflammasome Activation
    Cai, Xin
    Chen, Jueqi
    Xu, Hui
    Liu, Siqi
    Jiang, Qiu-Xing
    Halfmann, Randal
    Chen, Zhijian J.
    [J]. CELL, 2014, 156 (06) : 1207 - 1222
  • [6] Intracellular innate immune surveillance devices in plants and animals
    Jones, Jonathan D. G.
    Vance, Russell E.
    Dangl, Jeffery L.
    [J]. SCIENCE, 2016, 354 (6316)
  • [7] Modulation of Host Cell Biology by Plant Pathogenic Microbes
    Le Fevre, Ruth
    Evangelisti, Edouard
    Rey, Thomas
    Schornack, Sebastian
    [J]. ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 31, 2015, 31 : 201 - 229
  • [8] A Plant Immune Receptor Adopts a Two-Step Recognition Mechanism to Enhance Viral Effector Perception
    Li, Jia
    Huang, Haining
    Zhu, Min
    Huang, Shen
    Zhang, Wenhua
    Dinesh-Kumar, Savithramma P.
    Tao, Xiaorong
    [J]. MOLECULAR PLANT, 2019, 12 (02) : 248 - 262
  • [9] The Mechanism of Toxicity in HET-S/HET-s Prion Incompatibility
    Seuring, Carolin
    Greenwald, Jason
    Wasmer, Christian
    Wepf, Roger
    Saupe, Sven J.
    Meier, Beat H.
    Riek, Roland
    [J]. PLOS BIOLOGY, 2012, 10 (12)
  • [10] The structural basis of flagellin detection by NAIP5: A strategy to limit pathogen immune evasion
    Tenthorey, Jeannette L.
    Haloupek, Nicole
    Ramon Lopez-Blanco, Jose
    Grob, Patricia
    Adamson, Elise
    Hartenian, Ella
    Lind, Nicholas A.
    Bourgeois, Natasha M.
    Chacon, Pablo
    Nogales, Eva
    Vance, Russell E.
    [J]. SCIENCE, 2017, 358 (6365) : 888 - +