Osteoclastogenesis inhibitory Effect of Ergosterol Peroxide Isolated from Pleurotus eryngii

被引:0
作者
Yokoyama, Satoru [1 ]
Tran Hai Bang [1 ,2 ]
Shimizu, Kuniyoshi [1 ]
Kondo, Ryuichiro [1 ]
机构
[1] Kyushu Univ, Dept Agroenviromental Sci, Fac Agr, Fukuoka 8128581, Japan
[2] Hue Univ, Hue Coll Sci, Dept Chem, Thua Thien Hue, Vietnam
关键词
Ergosterol peroxide; Pleurotus eryngii; Osteoclastogenesis inhibitory effect; CYTOTOXIC ACTIVITIES; OSTEOPOROSIS; MUSHROOM; PREVENTION; CELLS;
D O I
暂无
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Ergosterol peroxide was isolated from the ethanol extract of neuron's eryngii as an inhibitor of osteoclast differentiation. This compound showed an inhibitory effect in a dose-dependent manner and an inhibition rate of up to 62% with low cytotoxicity, even at a concentration as low as 1.0 mu g/mL.
引用
收藏
页码:1163 / 1164
页数:2
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