Tools of the trade: psychophysiological interactions and functional connectivity

被引：565
作者：
O'Reilly, Jill X. [1 ]
Woolrich, Mark W. [1 ,2 ]
Behrens, Timothy E. J. [1 ,3 ]
Smith, Stephen M. [1 ]
Johansen-Berg, Heidi [1 ]
机构：
[1] Univ Oxford, John Radcliffe Hosp, Dept Clin Neurosci, FMRIB Ctr, Oxford OX3 9DU, England
[2] Univ Oxford, Warneford Hosp, Dept Psychiat, Oxford Ctr Human Brain Act OHBA, Oxford OX3 7JX, England
[3] UCL, Wellcome Trust Ctr Neuroimaging, London WC1N 3BG, England
来源：
SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE | 2012年 / 7卷 / 05期
基金：
英国医学研究理事会;
关键词：
psychophysiological interactions; PPI; functional connectivity; resting state; STRUCTURAL CONNECTIVITY; BRAIN; NETWORKS; FMRI;
D O I：
10.1093/scan/nss055
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Psychophysiological interactions (PPIs) analysis is a method for investigating task-specific changes in the relationship between activity in different brain areas, using functional magnetic resonance imaging (fMRI) data. Specifically, PPI analyses identify voxels in which activity is more related to activity in a seed region of interest (seed ROI) in a given psychological context, such as during attention or in the presence of emotive stimuli. In this tutorial, we aim to give a simple conceptual explanation of how PPI analysis works, in order to assist readers in planning and interpreting their own PPI experiments.
引用
收藏
页码：604 / 609
页数：6
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