Oxidative Palladium(II)-Catalyzed Dehydrogenative CH/CH Cross-Coupling of 2,3-Substituted Indolines with Arenes at the C7 Position

被引：80

作者：

Jiao, Lin-Yu ^{[1
]}

Oestreich, Martin ^{[1
]}

机构：

[1] Tech Univ Berlin, Inst Chem, D-10623 Berlin, Germany

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2013年 / 19卷 / 33期

关键词：

CH activation; cross-dehydrogenative coupling; dehydrogenation; homogeneous catalysis; palladium; CATALYZED ORTHO-ARYLATION; H BOND ACTIVATION; SODIUM PERSULFATE; FUNCTIONALIZATION; DERIVATIVES; RHODIUM; HETEROARENES; ANILIDES; INDOLES/PYRROLES; POLYFLUOROARENES;

D O I：

10.1002/chem.201302140

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Directed directing group: The C7 position of the indoline nucleus is difficult to address in C-H activation. An oxidative palladium(II) catalysis that allows for cross-dehydrogenative coupling in that position with activation of the C-H bond of the arene component is disclosed here. This C-H/C-H cross-coupling is applicable to various indolines acetylated at the nitrogen atom. Substitution at C2 is crucial for the C-H activation to occur at C7 (see scheme). © 2013 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：10845 / 10848

页数：4

共 63 条

[61] Pd-catalyzed ortho-arylation of phenylacetamides, benzamides, and anilides with simple arenes using sodium persulfate [J].