Herpes simplex virus: Drug resistance and new treatment options using natural products (Review)

被引:11
作者
Mundinger, Tabea Anne [2 ]
Efferth, Thomas [1 ]
机构
[1] German Canc Res Ctr, D-69120 Heidelberg, Germany
[2] Heidelberg Univ, Inst Pharm & Mol Biotechnol, D-6900 Heidelberg, Germany
关键词
anti-viral agents; chemotherapy; drug resistance; herpes simplex virus; natural products; pharmacognosy;
D O I
10.3892/mmr_00000001
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
As herpes simplex infections are very common worldwide, new treatment options are of high importance, especially for immunosuppressed individuals. Although the standard treatment options have shown high effectiveness for decades, the risk that drug resistance will emerge remains significant. It is therefore important that new drug targets and new treatments are investigated, not just in preliminary tests, but also in. vitro, in vivo and by clinical testing. One valuable source for new treatments is the abundance of molecules from natural products that have been shown to possess antiviral properties. Several potential candidates for the development of new anti-herpes drugs are discussed in this short review.
引用
收藏
页码:611 / 616
页数:6
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