Outcomes of First-Versus Second-Generation Drug-Eluting Stent Implanted for Right Coronary Artery Ostial Narrowing

被引：8

作者：

Sugihara, Ryuta ^{[1
]}

Ueda, Yasunori ^{[2
]}

Nishimoto, Yuji ^{[1
]}

Takahashi, Kuniaki ^{[1
]}

Murakami, Ayaka ^{[1
]}

Ueno, Keisuke ^{[1
]}

Takeda, Yasuharu ^{[1
]}

Hirata, Akio ^{[1
]}

Kashiwase, Kazunori ^{[1
]}

Higuchi, Yoshiharu ^{[1
]}

Yasumura, Yoshio ^{[1
]}

机构：

[1] Osaka Police Hosp, Div Cardiovasc, Osaka, Japan

[2] Osaka Natl Hosp, Div Cardiovasc, Osaka, Japan

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2017年 / 119卷 / 06期

关键词：

FOLLOW-UP; STENOSIS; REVASCULARIZATION; RESTENOSIS; DISEASE; LESIONS; METAANALYSIS; ANGIOPLASTY; PREDICTORS;

D O I：

10.1016/j.amjcard.2016.11.038

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Clinical outcome is generally poor when stents are implanted at right coronary artery ostial lesion (RCAos). We compared the clinical outcome between the first-generation drug eluting stent (first DES) and second-generation drug-eluting stent (second DES) used for RCAos. Consecutive 88 patients who underwent percutaneous coronary interventions of de novo RCAos using the first DES (33 patients) or second DES (55 patients) were analyzed. The incidence of major adverse cardiac events (MACE) defined as the composite of cardiac death, myocardial infarction attributed to right coronary artery, and target lesion revascularization within 2.5 years was compared. The incidence of MACE was significantly lower in second DES (11% vs 36%, p = 0.010) than that in the first DES. Multivariate analysis revealed use of second DES (odds ratio 0.24, 95% CI 0.11 to 0.93, p = 0.008) alone was significantly associated with MACE. In conclusion, second DES revealed better clinical outcome than the first DES when used in de novo RCAos. (C) 2016 Elsevier Inc. All rights reserved.

引用

页码：852 / 855

页数：4

共 19 条

[1]

[Anonymous], BMJ

[2] Restenosis of a sirolimus drug-elluting stent: Aorto-ostial involvement of the proximal right coronary artery [J].

Applegate, RJ ;

Draughn, T ;

Yarbrough, WD ;

Little, WC .

CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, 2006, 67 (03) :391-395

[3] Stent underexpansion and residual reference segment stenosis are related to stent thrombosis after sirolimus-eluting Stent implantation [J].

Fujii, K ;

Carlier, SG ;

Mintz, GS ;

Yang, YM ;

Moussa, I ;

Weisz, G ;

Dangas, G ;

Mehran, R ;

Lansky, AJ ;

Kreps, EM ;

Collins, M ;

Stone, GW ;

Lansky, AJ ;

Kreps, EM ;

Collins, M ;

Stone, GW ;

Moses, JW ;

Leon, MB .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2005, 45 (07) :995-998

[4] Clinical and angiographic outcome after sirolimus-eluting stent implantation in aorto-ostial lesions [J].

Iakovou, I ;

Ge, L ;

Michev, I ;

Sangiorgi, GM ;

Montorfano, M ;

Airoldi, F ;

Chieffo, A ;

Stankovic, G ;

Vitrella, G ;

Carlino, M ;

Corvaja, N ;

Briguori, C ;

Colombo, A .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2004, 44 (05) :967-971

[5] Comparison of balloon angioplasty versus debulking devices versus stenting in right coronary ostial lesions [J].

Jain, SP ;

Liu, MW ;

Dean, LS ;

Babu, R ;

Goods, CM ;

Yadav, JS ;

AlShaibi, KF ;

Mathur, A ;

Iyer, SS ;

Parks, M ;

Baxley, WA ;

Roubin, GS .

AMERICAN JOURNAL OF CARDIOLOGY, 1997, 79 (10) :1334-1338

[6] Sirolimus-eluting stent implantation for ostial right coronary artery lesions: Five-year outcomes from the j-Cypher registry [J].

Ko E. ;

Natsuaki M. ;

Toyofuku M. ;

Morimoto T. ;

Matsumura Y. ;

Oi M. ;

Motohashi Y. ;

Takahashi K. ;

Kawase Y. ;

Tanaka M. ;

Kitada M. ;

Yuzuki Y. ;

Tamura T. ;

Inoue K. ;

Mitsudo K. ;

Kimura T. .

Cardiovascular Intervention and Therapeutics, 2014, 29 (3) :200-208

[7] Clinical Outcome of Patients With Implantation of Second-Generation Drug-Eluting Stents in the Right Coronary Ostium: Insights From 2-Year Follow-up of the TWENTE Trial [J].

Lam, Ming Kai ;

Sen, Hanim ;

Tandjung, Kenneth ;

Loewik, Marije M. ;

Basalus, Mounir W. Z. ;

Mewes, Janne C. ;

Stoel, Martin G. ;

van Houwelingen, K. Gert ;

Linssen, Gerard C. M. ;

Ijzerman, Maarten J. ;

Doggen, Carine J. M. ;

von Birgelen, Clemens .

CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, 2015, 85 (04) :524-531

[8] Stent implantation in aorto-ostial lesions: long-term follow-up and predictors of outcome [J].

Luz, Andre ;

Hughes, Christine ;

Magalhaes, Rui ;

Bisceglia, Teodoro ;

Descoutures, Fleur ;

Tamamm, Khalid ;

Tchetche, Didier ;

Sauguet, Antoine ;

Farah, Bruno ;

Fajadet, Jean .

EUROINTERVENTION, 2012, 7 (09) :1069-1076

[9] Effectiveness of rotational atherectomy of right coronary artery ostial stenosis [J].

Motwani, JG ;

Raymond, RE ;

Franco, I ;

Ellis, SG ;

Whitlow, PL .

AMERICAN JOURNAL OF CARDIOLOGY, 2000, 85 (05) :563-567

[10] Outcomes of the largest multi-center trial stratified by the presence of diabetes mellitus comparing sirolimus-eluting stents (SES) and paclitaxel-eluting stents (PES) in patients with coronary artery disease. The Japan drug-eluting stents evaluation: a randomized trial (J-DESsERT) [J].

Nakamura M. ;

Muramatsu T. ;

Yokoi H. ;

Okada H. ;

Ochiai M. ;

Suwa S. ;

Hozawa H. ;

Kawai K. ;

Awata M. ;

Mukawa H. ;

Fujita H. ;

Shiode N. ;

Asano R. ;

Tsukamoto Y. ;

Yamada T. ;

Yasumura Y. ;

Ohira H. ;

Miyamoto A. ;

Takashima H. ;

Ogawa T. ;

Matsuyama Y. ;

Nanto S. .

Cardiovascular Intervention and Therapeutics, 2015, 30 (2) :103-114

← 1 2 →