Epithelioid hemangioendothelioma of the liver: The role of hepatobiliary phase imaging for the preoperative diagnosis and qualification of patients for liver transplantation - preliminary experience

被引:0
作者
Cieszanowski, Andrzej [1 ]
Pacho, Ryszard [1 ]
Anysz-Grodzicka, Agnieszka [1 ]
Gornicka, Barbara [2 ]
Piotr, Remiszewski [3 ]
Maj, Edyta [1 ]
Grudzinski, Ireneusz P. [4 ]
Zieniewicz, Krzysztof [3 ]
Oldakowska-Jedynak, Urszula [3 ]
Rowinski, Olgierd [1 ]
Krawczyk, Marek [3 ]
机构
[1] Med Univ Warsaw, Dept Clin Radiol 2, PL-02097 Warsaw, Poland
[2] Med Univ Warsaw, Dept Pathol Anat, PL-02097 Warsaw, Poland
[3] Med Univ Warsaw, Chair & Dept Gen Transplant & Liver Surg, PL-02097 Warsaw, Poland
[4] Med Univ Warsaw, Dept Toxicol, PL-02097 Warsaw, Poland
关键词
liver neoplasms; epithelioid hemangioendothelioma; MRI; hepatobiliary contrast agents; liver transplantation; GADOBENATE DIMEGLUMINE; MR; CT; LESIONS;
D O I
暂无
中图分类号
R61 [外科手术学];
学科分类号
摘要
Background: The aim of this study was to determine if the appearance of hepatic epithelioid hemangioendothelioma (HEHE) on state-of-the-art MRI including hepatocyte phase after administration of hepatobiliary contrast agent can facilitate preoperative diagnosis and identification of potential candidates for liver transplantation. Material/Methods: The study group comprised 6 patients with pathologically confirmed HEHE. Analysis included signal characteristics of 55 tumor nodules (maximum of 10 lesions per patient) on T2-weighted images, dynamic contrast-enhanced, 5-minute delayed, and hepatobiliary phase images. Results: The most common feature of HEHE, observed in 84% of lesions, was progressive contrast-enhancement, followed by subcapsular location (66%), confluent appearance (60%) and hyper-or isointensity on hepatobiliary phase images (53%). In 5 of 6 patients, capsular retraction was observed. Conclusions: The appearance of HEHE on hepatobiliary phase images was variable, but examined tumors often demonstrated hyper-or isointensity, most probably due to prolonged retention of contrast material. These features, along with typical morphology (subcapsular, confluent nodules, with progressive enhancement and capsular retraction), may contribute to correct diagnosis and recognition of potential candidates for liver transplantation.
引用
收藏
页码:424 / 433
页数:10
相关论文
共 29 条
[1]   Characterization of focal liver lesions by ADC measurements using a respiratory triggered diffusion-weighted single-shot echo-planar MR imaging technique [J].
Bruegel, Melanie ;
Holzapfel, Konstantin ;
Gaa, Jochen ;
Woertler, Klaus ;
Waldt, Simone ;
Kiefer, Berthold ;
Stemmer, Alto ;
Ganter, Carl ;
Rummeny, Ernst J. .
EUROPEAN RADIOLOGY, 2008, 18 (03) :477-485
[2]   Hepatic epithelioid hemangioendothelioma: findings at CT and MRI including preliminary observations at diffusion-weighted echo-planar imaging [J].
Bruegel, Melanie ;
Muenzel, Daniela ;
Waldt, Simone ;
Specht, Katja ;
Rummeny, Ernst J. .
ABDOMINAL IMAGING, 2011, 36 (04) :415-424
[3]   Characterization of focal liver lesions using quantitative techniques: comparison of apparent diffusion coefficient values and T2 relaxation times [J].
Cieszanowski, Andrzej ;
Anysz-Grodzicka, Agnieszka ;
Szeszkowski, Wojciech ;
Kaczynski, Bartosz ;
Maj, Edyta ;
Gornicka, Barbara ;
Grodzicki, Mariusz ;
Grudzinski, Ireneusz P. ;
Stadnik, Anna ;
Krawczyk, Marek ;
Rowinski, Olgierd .
EUROPEAN RADIOLOGY, 2012, 22 (11) :2514-2524
[4]   HEPATIC EPITHELIOID HEMANGIOENDOTHELIOMA - REPORT OF 5 CASES [J].
FURUI, S ;
ITAI, Y ;
OHTOMO, K ;
YAMAUCHI, T ;
TAKENAKA, E ;
IIO, M ;
IBUKURO, K ;
SHICHIJO, Y ;
INOUE, Y .
RADIOLOGY, 1989, 171 (01) :63-68
[5]   Liver diffusion-weighted MR imaging: the tower of Babel? [J].
Guiu, Boris ;
Cercueil, Jean-Pierre .
EUROPEAN RADIOLOGY, 2011, 21 (03) :463-467
[6]   EPITHELIOID HEMANGIOENDOTHELIOMA OF THE LIVER - A CLINICOPATHOLOGIC AND FOLLOW-UP-STUDY OF 32 CASES [J].
ISHAK, KG ;
SESTERHENN, IA ;
GOODMAN, MZD ;
RABIN, L ;
STROMEYER, FW .
HUMAN PATHOLOGY, 1984, 15 (09) :839-852
[7]  
Kehagias DT, 2000, HEPATO-GASTROENTEROL, V47, P1711
[8]  
Kim Kyoung Ah, 2006, AJR Am J Roentgenol, V187, pW481, DOI 10.2214/AJR.05.0659
[9]   Distinguishing hepatic metastases from hemangiomas - Qualitative and quantitative diagnostic performance through dual echo respiratory-triggered fast spin echo magnetic resonance imaging [J].
Kim, YH ;
Saini, S ;
Blake, MA ;
Harisinghani, M ;
Chiou, YY ;
Lee, WJ ;
Yu, JS ;
Hahn, PF .
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 2005, 29 (05) :571-579
[10]   Hepatic Uptake of the Magnetic Resonance Imaging Contrast Agent Gd-EOB-DTPA: Role of Human Organic Anion Transporters [J].
Leonhardt, Mirko ;
Keiser, Markus ;
Oswald, Stefan ;
Kuhn, Jens ;
Jia, Jia ;
Grube, Markus ;
Kroemer, Heyo K. ;
Siegmund, Werner ;
Weitschies, Werner .
DRUG METABOLISM AND DISPOSITION, 2010, 38 (07) :1024-1028