Updated perspectives on the cytosolic sulfotransferases (SULTs) and SULT-mediated sulfation

被引：70
作者：
Suiko, Masahito [1 ]
Kurogi, Katsuhisa [1 ,2 ]
Hashiguchi, Takuyu [1 ]
Sakakibara, Yoichi [1 ]
Liu, Ming-Cheh [2 ]
机构：
[1] Miyazaki Univ, Dept Biochem & Appl Biosci, Fac Agr, Miyazaki, Japan
[2] Univ Toledo, Dept Pharmacol, Coll Pharm & Pharmaceut Sci, 2801 W Bancroft St, Toledo, OH 43606 USA
来源：
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2017年 / 81卷 / 01期
基金：
日本学术振兴会; 美国国家卫生研究院;
关键词：
sulfotransferase; 3-phosphoadenosine-5-phosphosulfate; Phase II; detoxifying enzymes; CATECHOL-O-METHYLTRANSFERASE; MOLECULAR-CLONING; THYROID-HORMONE; FUNCTIONAL-CHARACTERIZATION; HUMAN FETAL; ESTROGEN SULFOTRANSFERASE; CDNA CLONING; HYDROXYSTEROID SULFOTRANSFERASES; TISSUE DISTRIBUTION; OXIDATIVE STRESS;
D O I：
10.1080/09168451.2016.1222266
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The cytosolic sulfotransferases (SULTs) are Phase II detoxifying enzymes that mediate the sulfate conjugation of numerous xenobiotic molecules. While the research on the SULTs has lagged behind the research on Phase I cytochrome P-450 enzymes and other Phase II conjugating enzymes, it has gained more momentum in recent years. This review aims to summarize information obtained in several fronts of the research on the SULTs, including the range of the SULTs in different life forms, concerted actions of the SULTs and other Phase II enzymes, insights into the structure-function relationships of the SULTs, regulation of SULT expression and activity, developmental expression of SULTs, as well as the use of a zebrafish model for studying the developmental pharmacology/toxicology.
引用
收藏
页码：63 / 72
页数：10
相关论文
共 122 条
[41]   The complexity of the Nrf2 pathway: beyond the antioxidant response [J].
Huang, Ying ;
Li, Wenji ;
Su, Zheng-yuan ;
Kong, Ah-Ng Tony .
JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2015, 26 (12) :1401-1413
[42]   On the sulfation and methylation of Catecholestrogens in human mammary epithelial cells and breast cancer cells [J].
Hui, Ying ;
Yasuda, Shin ;
Liu, Ming-Yih ;
Wu, Yi-yong ;
Liu, Ming-Cheh .
BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2008, 31 (04) :769-773
[43]   Inhibitory Effects of Nitrative Stress on the Sulfation of 17β-Estradiol and 4-Methoxyestradiol by Human MCF 10A Mammary Epithelial Cells [J].
Hui, Ying ;
Yasuda, Tomoko ;
Yasuda, Shin ;
Liu, Ming-Yih ;
Sakakibara, Yoichi ;
Suiko, Masahito ;
Wall, Katherine Ann ;
Liu, Ming-Cheh .
BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2010, 33 (09) :1633-1637
[44]   ESTROGEN AND PHENOL SULFOTRANSFERASE ACTIVITIES IN HUMAN FETAL LUNG [J].
JONES, AL ;
HUME, R ;
BAMFORTH, KJ ;
COUGHTRIE, MWH .
EARLY HUMAN DEVELOPMENT, 1992, 28 (01) :65-77
[45]   Crystal structure of estrogen sulphotransferase [J].
Kakuta, Y ;
Pedersen, LG ;
Carter, CW ;
Negishi, M ;
Pedersen, LC .
NATURE STRUCTURAL BIOLOGY, 1997, 4 (11) :904-908
[46]   Cloning, sequence analysis, and characterization of the astA gene encoding an arylsulfate sulfotransferase from Citrobacter freundii [J].
Kang, JW ;
Jeong, YJ ;
Kwon, AR ;
Yun, HJ ;
Kim, DH ;
Choi, EC .
ARCHIVES OF PHARMACAL RESEARCH, 2001, 24 (04) :316-322
[47]   THE PRENATAL AND POSTNATAL-DEVELOPMENT OF UDP-GLUCURONYLTRANSFERASE ACTIVITY TOWARDS BILIRUBIN AND THE EFFECT OF PREMATURE BIRTH ON THIS ACTIVITY IN THE HUMAN-LIVER [J].
KAWADE, N ;
ONISHI, S .
BIOCHEMICAL JOURNAL, 1981, 196 (01) :257-260
[48]   THE ROLE OF INTESTINAL FLORA IN METABOLISM OF PHENOLIC SULFATE ESTERS [J].
KIM, DH ;
KOBASHI, K .
BIOCHEMICAL PHARMACOLOGY, 1986, 35 (20) :3507-3510
[49]   Suppression of DHEA sulfotransferase (Sult2A1) during the acute-phase response [J].
Kim, MS ;
Shigenaga, J ;
Moser, A ;
Grunfeld, C ;
Feingold, KR .
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2004, 287 (04) :E731-E738
[50]   Nrf2 the rescue: Effects of the antioxidative/electrophilic response on the liver [J].
Klaassen, Curtis D. ;
Reisman, Scott A. .
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2010, 244 (01) :57-65
12345678910