Dry Mouth: An Overlooked Autonomic Symptom of Parkinson's Disease

被引：23

作者：

Cersosimo, Maria G. ^{[1
]}

Raina, Gabriela B. ^{[1
]}

Calandra, Cristian R. ^{[1
]}

Pellene, Alejandro ^{[1
]}

Gutierrez, Cristiam ^{[1
]}

Micheli, Federico E. ^{[1
]}

Benarroch, Eduardo E. ^{[2
]}

机构：

[1] Univ Buenos Aires, Parkinsons Dis & Movement Disorders Unit, Hosp Clin Jose de San Martin, Buenos Aires, DF, Argentina

[2] Mayo Clin, Dept Neurol, Rochester, MN USA

来源：

JOURNAL OF PARKINSONS DISEASE | 2011年 / 1卷 / 02期

关键词：

Parkinson's disease; hyposialorrhea; xerostomia; dry mouth; drooling; GASTROINTESTINAL DYSFUNCTION; SALIVARY SECRETION; PREVALENCE;

D O I：

10.3233/JPD-2011-11021

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

There is involvement of salivary glands by alpha-synuclein pathology in PD. However, the prevalence of dry mouth has not been systematically assessed in these patients. We studied 97 PD patients and 86 controls using a structured questionnaire. Dry mouth was reported by 60.8% of PD patients and 27.9% of controls (p < 0.0001). Dry mouth and drooling coexisted in 30% of cases. Only 12% of patients had reported dry mouth to their physicians. Dry mouth is a frequent but underreported symptom and may be an early manifestation of autonomic involvement in PD.

引用

页码：169 / 173

页数：5

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