Testicular sperm extraction in a single cancerous testicle in patients with azoospermia: a case report

被引:25
作者
Descombe, Laure [2 ]
Chauleur, Celine [2 ]
Gentil-Perret, Anne [3 ]
Aknin-Seifer, Isabelle [1 ]
Tostain, Jacques [4 ]
Levy, Rachel [1 ]
机构
[1] Hop Nord St Etienne, Reprod Biol Lab, F-42055 St Etienne, France
[2] Hop Nord St Etienne, Dept Obstet Gynecol, F-42055 St Etienne, France
[3] Hop Nord St Etienne, Dept Anatomopathol, F-42055 St Etienne, France
[4] Hop Nord St Etienne, Dept Urol, F-42055 St Etienne, France
关键词
Azoospermia; testicular cancer; cryopreservation; fertility; ICSI; TESE;
D O I
10.1016/j.fertnstert.2007.07.1308
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: To optimize the management of patients with cancer in a single testis and azoospermia. Design: Case report. Setting: Reproductive biology department. Patient(s): Two male patients referred in an emergency context for gamete cryopreservation before castration for cancer in a single testis; the patients were azoospermic before any sterilizing treatment. Intervention(s): Testicular sperm extraction (TESE) was carried out synchronously with orchiectomy, allowing the cryopreservation of testicular spermatozoa. Main Outcome Measure(s): One year after the end of the cancer treatment, thawed testicular spermatozoa were successfully used in an intracytoplasmic sperm injection procedure. A twin pregnancy was obtained, and a healthy boy and girl were born. Conclusion(s): TESE and cryopreservation could be offered to every patient with cancer in a single testis and azoospermia. (Fertil Steril (R) 2008; 90: 443. e1-e4. (C) 2008 by American Society for Reproductive Medicine.)
引用
收藏
页码:443.e1 / 443.e4
页数:4
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