Audit of Physicians' Adherence to the Antibiotic Policy Guidelines in Kuwait

被引:13
作者
Aly, Nasser Y. [1 ,3 ]
Omar, Abeer A. [1 ,5 ]
Badawy, Dina A. [1 ,6 ]
Al-Mousa, Haifa H. [1 ]
Sadek, Ali A. [2 ,4 ]
机构
[1] Minist Hlth, Directorate Infect Control, Kuwait, Kuwait
[2] Minist Hlth, Directorate Hlth Informat & Med Records, Kuwait, Kuwait
[3] Univ Alexandria, High Inst Publ Hlth, Dept Trop Med & Hyg, Alexandria, Egypt
[4] Univ Alexandria, High Inst Publ Hlth, Fac Med, Dept Community Med, Alexandria, Egypt
[5] Univ Alexandria, High Inst Publ Hlth, Dept Microbiol, Alexandria, Egypt
[6] Ain Shams Univ, Fac Med, Dept Clin Pathol, Cairo, Egypt
关键词
Antibiotic policy guidelines; adherence; Rational prescribing; Kuwait; PROPHYLAXIS; MISUSE; CARE; INFECTIONS; PNEUMONIA; HOSPITALS; BARRIERS; PROGRAM;
D O I
10.1159/000334769
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: To audit physicians' adherence to the local antibiotic policy guidelines in government hospitals in Kuwait. Materials and Methods: The study was a retrospective review of patient records in nine hospitals between July 1 and December 31, 2008. Clinical notes and medication charts of the latest hospital admissions were checked for antibiotic prescribing. On the audit form, aspects of the prescribed antibiotic were benchmarked to the hospital antibiotic policy guidelines to evaluate adherence. Results: Of 2,232 reviewed records, 1,112 (49.8%) patients had 1,528 antibiotic prescriptions. Patients who received antibiotics were significantly younger than those who did not (median age: 26.3 vs. 29.8 years, p < 0.001) and their hospital stay was significantly longer (median: 4 vs. 2 days, p < 0.001). The choice of an antibiotic was appropriate and matched the policy in 806 (52.7%) prescriptions. Of such appropriate antibiotics, adherence to route of administration was observed in 768/806 (95.3%), to dose in 758 (94%), to frequency in 746 (92.6%) and to duration in 608 (75.4%). Full adherence to all aspects of antibiotic choice, dose, route, frequency and duration was achieved in 464 (30.4%) prescriptions. In 382 (25%), the antibiotics administered were not indicated. Conclusion: There was low adherence to the local antibiotic policy guidelines. Physicians' antibiotic prescribing practices should be optimized. Adherence to, and update of, the policy is recommended. Copyright (C) 2012 S. Karger AG, Basel
引用
收藏
页码:310 / 317
页数:8
相关论文
共 29 条
[1]   Nosocomial infections and misuse of antibiotics in a provincial community hospital, Saudi Arabia [J].
Al-Ghamdi, S ;
Gedebou, M ;
Bilal, NE .
JOURNAL OF HOSPITAL INFECTION, 2002, 50 (02) :115-121
[2]   Misuse of antimicrobial agents in neonatal units: A cross-sectional survey in Kuwait [J].
Al-Sawan, RMZ ;
Soni, AL ;
Al-Saleh, Q ;
Al-Alfy, AA ;
Al-Essa, M ;
Rajaramu, U ;
Deverajan, LV .
MEDICAL PRINCIPLES AND PRACTICE, 1999, 8 (02) :119-125
[3]  
ASWAPOKEE N, 1990, REV INFECT DIS, V12, P136
[4]   Identifying barriers to the rapid administration of appropriate antibiotics in community-acquired pneumonia [J].
Barlow, Gavin ;
Nathwani, Dilip ;
Myers, Elizabeth ;
Sullivan, Frank ;
Stevens, Nicola ;
Duffy, Rebecca ;
Davey, Peter .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2008, 61 (02) :442-451
[5]   Effect of antibiotic prescribing in primary care on antimicrobial resistance in individual patients: systematic review and meta-analysis [J].
Costelloe, Ceire ;
Metcalfe, Chris ;
Lovering, Andrew ;
Mant, David ;
Hay, Alastair D. .
BMJ-BRITISH MEDICAL JOURNAL, 2010, 340 :1120
[6]   Interventions to improve antibiotic prescribing practices for hospital inpatients [J].
Davey, Peter ;
Brown, Erwin ;
Charani, Esmita ;
Fenelon, Lynda ;
Gould, Ian M. ;
Holmes, Alison ;
Ramsay, Craig R. ;
Wiffen, Philip J. ;
Wilcox, Mark .
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2013, (04)
[7]  
Davis DA, 1997, CAN MED ASSOC J, V157, P408
[8]   Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship [J].
Dellit, Timothy H. ;
Owens, Robert C. ;
McGowan, John E., Jr. ;
Gerding, Dale N. ;
Weinstein, Robert A. ;
Burke, John P. ;
Huskins, W. Charles ;
Paterson, David L. ;
Fishman, Neil O. ;
Carpenter, Christopher F. ;
Brennan, P. J. ;
Billeter, Marianne ;
Hooton, Thomas M. .
CLINICAL INFECTIOUS DISEASES, 2007, 44 (02) :159-177
[9]   Multicentre evaluation of prescribing concurrence with anti-infective guidelines: epidemiological assessment of indicators [J].
Fijn, R ;
Chow, MC ;
Schuur, PMH ;
De Jong-Van den Berg, LTW ;
Brouwers, JRBJ .
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, 2002, 11 (05) :361-372
[10]  
Fonseca Laura Guimarães, 2004, Braz J Infect Dis, V8, P272, DOI 10.1590/S1413-86702004000400002