A Vinyl Chloride-exposed Worker with an Adrenal Gland Angiosarcoma: A Case Report

被引：13
作者：
Criscuolo, Mario [1 ]
Valerio, Jacqueline [1 ]
Gianicolo, Maria Elena [3 ]
Gianicolo, Emilio A. L. [4 ,5 ]
Portaluri, Maurizio [2 ,4 ]
机构：
[1] Perrino Hosp, Dept Pathol, Brindisi, Italy
[2] Perrino Hosp, Dept Radiotherapy, Brindisi, Italy
[3] Euromediterranean Biomed Sci Inst ISBEM, Brindisi, Italy
[4] CNR, Inst Clin Physiol IFC CNR, I-00185 Rome, Italy
[5] Johannes Gutenberg Univ Mainz, Inst Med Biometrie Epidemiol & Informat, Mainz, Germany
来源：
INDUSTRIAL HEALTH | 2014年 / 52卷 / 01期
关键词：
Adrenal angiosarcoma; Vinyl chloride; Extraepatic; PRIMARY EPITHELIOID ANGIOSARCOMA; HEPATIC ANGIOSARCOMA; POLYVINYL-CHLORIDE; LIVER-DISEASE; HEMANGIOSARCOMA; INTOXICATION; THOROTRAST; MORTALITY; CARCINOMA; SARCOMA;
D O I：
10.2486/indhealth.2013-0044
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
Adrenal epithelioidangiosarcoma (AEA) is a rare neoplasm that accounts for less than 1% of sarcomas. Due to its rarity, it can easily be misdiagnosed, both by the clinician and the pathologist. Data on the patient's occupational history was collected and analyzed. The bibliographic data was found on the PUBMED bibliographic search site after entering the word "extrahepaticangiosarcoma". We report a case of adrenal epithelioidangiosarcoma (AEA) in a 68 yr-old Caucasian male factory worker exposed to Vinyl Chloride (VC) for 15 yr. He underwent surgery, chemotherapy and radiotherapy. Hepatic angiosarcoma is a known consequence of VC exposure, but occupational causality of extra-hepatic angiosarcoma is controversial. Extra-hepatic angiosarcomas have been reported in VC workers, but never AEA. Cancerogenic effects of VC involve all endothelial areas of the body and extra-hepatic endothelial tumors may also be caused by this substance. This is the first published report of AEA diagnosed in a worker exposed to VC.
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页码：66 / 70
页数：5
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