82Sr purification procedure using Chelex-100 resin

被引：4
作者：
Alliot, C. [1 ,2 ]
Audouin, N. [1 ]
Bonraisin, A. C. [1 ]
Bosse, V. [1 ,2 ]
Laize, J. [1 ]
Bourdeau, C. [1 ]
Mokili, B. M. [1 ,3 ]
Michel, N. [1 ,3 ]
Haddad, F. [1 ,3 ]
机构：
[1] GIP Arronax, F-44817 St Herblain, France
[2] Inst Biol, Ctr Rech Cancerol Nantes Angers, Inserm U892, F-44035 Nantes 01, France
[3] Univ Nantes, IN2P3 CNRS, Ecole Mines Nantes, Subatech Lab,UMR 6457, F-44300 Nantes, France
来源：
APPLIED RADIATION AND ISOTOPES | 2013年 / 74卷
关键词：
Sr-82; Rb-82; Purification; Flow rate; Automation; GENERATOR; RB-82; ENERGY;
D O I：
10.1016/j.apradiso.2012.10.020
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Rb-82 is a positron-emitting radionuclide widely used in nuclear cardiology. One great advantage is its availability through a generator loaded with Sr-82. Sr-82 can be produced in a high energy cyclotron by irradiating rubidium chloride target with proton beam. In this paper, we present an extensive study (elution profiles, effect of the elution flow rate) on the use of Chelex-100 resin and ammonia buffer. No significant effect of flow rate was evidenced between 1 and 10 mL/min leading us to propose a purification process which can be easily automated. (C) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码：56 / 60
页数：5
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