Synthesis of tert-Butyl Peroxyacetals from Benzyl, Allyl, or Propargyl Ethers via Iron-Promoted C-H Bond Functionalization

被引：33

作者：

Iwata, Satoshi ^{[1
]}

Hata, Takeshi ^{[1
]}

Urabe, Hirokazu ^{[1
]}

机构：

[1] Tokyo Inst Technol, Dept Biomol Engn, Grad Sch Biosci & Biotechnol, Midori Ku, Yokohama, Kanagawa 2268501, Japan

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2012年 / 354卷 / 18期

关键词：

tert-butyl hydroperoxide; C?H functionalization; iron; oxidation; peroxyacetals; peroxyorthoesters; CYTOCHROME-P-450 TYPE OXIDATION; SILYL KETENE ACETALS; SATURATED-HYDROCARBONS; CATALYZED OXIDATION; CYCLIC ACETALS; ACTIVATION; ADJACENT; HYDROPEROXIDE; ALPHA; NITROGEN;

D O I：

10.1002/adsc.201200410

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

When benzyl, allyl, and propargyl ethers were treated with tert-butyl hydroperoxide and a catalytic amount of iron(III) acetylacetonate, tert-butyl peroxyacetals were produced in good to excellent yields, via C?H bond functionalization. This method is also applicable to ethylene acetals of unsaturated aldehydes to give peroxyorthoesters.

引用

页码：3480 / 3484

页数：5

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