Synthesis of a maradolipid without using protecting groups

被引：10
作者：
Csuk, Rene [1 ]
Schultheiss, Andrea [1 ]
Sommerwerk, Sven [1 ]
Kluge, Ralph [1 ]
机构：
[1] Univ Halle Wittenberg, D-06120 Halle, Saale, Germany
来源：
TETRAHEDRON LETTERS | 2013年 / 54卷 / 18期
关键词：
Maradolipid; Chemoenzymatic trans-esterification; Trehalose; CAENORHABDITIS-ELEGANS; CORD FACTOR; DIACYLTREHALOSE GLYCOLIPIDS; TREHALOSE ESTERS; DAUER LARVA; TUBERCULOSIS; ANALOGS;
D O I：
10.1016/j.tetlet.2013.02.076
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A convenient route has been developed to synthesize 6-O-mono- and 6,6'-di-O-acyl symmetrical and unsymmetrical (un)-symmetrically trehalose derivatives from trehalose using a combination of enzymic and nonenzymic reactions. Thus, a typical maradolipid was accessed in two-steps. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码：2274 / 2276
页数：3
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