The role of serine/threonine kinases in T-cell activation

被引：14

作者：

Matthews, Sharon A. ^{[1
]}

Cantrell, Doreen A. ^{[1
]}

机构：

[1] Univ Dundee, Div Cell Biol & Immunol, Wellcome Trust Bioctr, Dundee DD1 5EH, Scotland

来源：

CURRENT OPINION IN IMMUNOLOGY | 2006年 / 18卷 / 03期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/j.coi.2006.03.006

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Signalling through serine/threonine kinases is a key mechanism that regulates immune cell development, activation and effector functions. An emerging theme is that serine kinases do not act in isolation, but function in a complex overlapping network. Understanding the molecular targets of serine kinases as well as their links to other serine kinases is key to advancing our understanding of the intracellular signalling pathways that link immune receptors with the gene transcriptional programs that control the immune system in vivo.

引用

页码：314 / 320

页数：7

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