Influence of effector molecules on the CD8+ T cell response to infection

被引：80
作者：
Harty, JT
Badovinac, VP
机构：
[1] Univ Iowa, Dept Microbiol, Iowa City, IA 52242 USA
[2] Univ Iowa, Interdisciplinary Grad Program Immunol, Iowa City, IA 52242 USA
来源：
CURRENT OPINION IN IMMUNOLOGY | 2002年 / 14卷 / 03期
关键词：
D O I：
10.1016/S0952-7915(02)00333-3
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Expansion and contraction of antigen-specific CD8(+) T cells after infection or vaccination results in stable memory, Recent evidence demonstrates that anti-microbial effector molecules such as perforin and IFN-gamma regulate specific aspects of CD8(+) T cell homeostasis by mechanisms that may be dependent or independent of pathogen clearance.
引用
收藏
页码：360 / 365
页数：6
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