Tailoring elastic properties of PLGA/TiO2 biomaterials

被引：11

作者：

Fiedler, T. ^{[1
]}

Belova, I. V. ^{[1
]}

Murch, G. E. ^{[1
]}

Roether, J. A. ^{[2
]}

Boccaccini, A. R. ^{[3
]}

机构：

[1] Univ Newcastle, Univ Ctr Mass & Thermal Transport Engn Mat, Sch Engn, Callaghan, NSW 2308, Australia

[2] Univ Erlangen Nurnberg, Dept Mat Sci & Engn, Inst Polymer Mat, D-91058 Erlangen, Germany

[3] Univ Erlangen Nurnberg, Inst Biomat, Dept Mat Sci & Engn, D-91058 Erlangen, Germany

来源：

COMPUTATIONAL MATERIALS SCIENCE | 2012年 / 61卷

关键词：

Biomaterial; Particle reinforced composite; Elastic properties; Finite element analysis; Analytical analysis; TISSUE ENGINEERING SCAFFOLDS; BONE; NANOCOMPOSITES; BIOACTIVITY; MODULUS;

D O I：

10.1016/j.commatsci.2012.04.043

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

This paper addresses the mechanical properties of titania reinforced poly(lactic-co-glycolic acid) (PLGA), a composite material being considered for applications in bone tissue engineering. Titania nano-particles are added to the PLGA matrix for the improvement of mechanical properties. By changing the fraction of reinforcement, mechanical properties can be adjusted to match values of the surrounding tissue for mechanical compatibility. Numerical finite element and theoretical analyses were conducted to obtain simple design guidelines for tailoring the mechanical properties of these promising composites. (c) 2012 Elsevier B.V. All rights reserved.

引用

页码：283 / 286

页数：4

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