Piezoelectric-transducer-based miniature catheter for ultrahigh-speed endoscopic optical coherence tomography

被引：25
作者：
Tsai, Tsung-Han [1 ]
Potsaid, Benjamin [1 ,2 ]
Kraus, Martin F. [1 ,3 ,4 ]
Zhou, Chao [1 ]
Tao, Yuankai K. [1 ]
Hornegger, Joachim [3 ,4 ]
Fujimoto, James G. [1 ]
机构：
[1] MIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
[2] Thorlabs Inc, Adv Imaging Grp, Newton, NJ USA
[3] Univ Erlangen Nurnberg, Pattern Recognit Lab, Nurnberg, Germany
[4] Univ Erlangen Nurnberg, Grad Sch Adv Opt Technol, Nurnberg, Germany
来源：
BIOMEDICAL OPTICS EXPRESS | 2011年 / 2卷 / 08期
关键词：
MIRROR; ENDOMICROSCOPY; MICROSCOPY; SCANS; 2ND;
D O I：
10.1364/BOE.2.002438
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
We developed a piezoelectric-transducer-(PZT) based miniature catheter with an outer diameter of 3.5 mm for ultrahigh-speed endoscopic optical coherence tomography (OCT). A miniaturized PZT bender actuates a fiber and the beam is scanned through a GRIN lens and micro-prism to provide high-speed, side-viewing capability. The probe optics can be pulled back over a long distance to acquire three-dimensional (3D) data sets covering a large area. Imaging is performed with 11 mu m axial resolution in air (8 mu m in tissue) and 20 mu m transverse resolution, at 960 frames per second with a Fourier domain mode-locked laser operating at 480 kHz axial scan rate. Using a high-speed data acquisition system, endoscopic OCT imaging of the rabbit esophagus and colon in vivo and human colon specimens ex vivo is demonstrated. (C) 2011 Optical Society of America
引用
收藏
页码：2438 / 2448
页数：11
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