Greater genetic diversity is needed in human pluripotent stem cell models

被引：30

作者：

Ghosh, Sulagna ^{[1
,2
]}

Nehme, Ralda ^{[1
,2
]}

Barrett, Lindy E. ^{[1
,2
]}

机构：

[1] Broad Inst MIT & Harvard, Stanley Ctr Psychiat Res, Cambridge, MA 02142 USA

[2] Harvard Univ, Dept Stem Cell & Regenerat Biol, Cambridge, MA 02138 USA

来源：

NATURE COMMUNICATIONS | 2022年 / 13卷 / 01期

关键词：

IPSC LINES; PROMISE; DISEASE;

D O I：

10.1038/s41467-022-34940-z

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

While there are a growing number of human pluripotent stem cell repositories, genetic diversity remains limited in most collections and studies. Here, we discuss the importance of incorporating diverse ancestries in these models to improve equity and accelerate biological discovery.

引用

页数：7

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