Indole-3-carbaldehydes Arylhydrazones as Multisite C-Nucleophiles in the Reactions with Quinazoline

被引：1

作者：

Azev, Yu. A. ^{[1
]}

Koptyaeva, O. S. ^{[1
]}

Eltsov, O. S. ^{[1
]}

Yakovleva, Yu. A. ^{[1
]}

Tsmokalyuk, A. N. ^{[1
]}

Ivoilova, A. V. ^{[1
]}

Seliverstova, E. A. ^{[1
]}

Pospelova, T. A. ^{[1
]}

Bakulev, V. A. ^{[1
]}

机构：

[1] Ural Fed Univ, Ekaterinburg 620002, Russia

来源：

RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2020年 / 90卷 / 09期

关键词：

arylhydrazones; indole-3-carbaldehydes; C; C-coupling; quinazoline; trifluoro hydrazides; DENSITY-FUNCTIONAL THEORY;

D O I：

10.1134/S1070363220090030

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

C,C-Coupling of indole-3-carbaldehyde arylhydrazones with quinazoline in trifluoroacetic acid has occurred at position 5 or 7 ' of the hydrazone molecule and has afforded the sigma-adducts. The C,C-coupling has been accompanied by a change in theE-configuration of the C=N bond of the starting hydrazones to theZ-configuration in the formed quinazoline trifluoroacetyl hydrazides.

引用

页码：1601 / 1610

页数：10

共 23 条

[1]

Anastas P.T., 1998, GREEN CHEM THEORY PR, P516

[2]

Aniszewski T, 2015, ALKALOIDS

[3] Chemical Characteristics, Synthetic Methods, and Biological Potential of Quinazoline and Quinazolinone Derivatives [J].