Optical and Visual Quality of the Visian Implantable Collamer Lens Using an Adaptive-Optics Visual Simulator

PURPOSE: To evaluate visual and optical quality of the implantable collamer lens for different powers and sizes of incision surgery. DESIGN: Prospective study in humans. METHODS: An adaptive optics visual simulator was used to measure 3 powers of implantable collamer lenses and simulate the implantable collamer lens wavefront aberration's pattern for small- and large-incision surgery. Visual acuity (VA) and contrast sensitivity were measured in 11 observers for 3- and 5-mm pupils. Modulation transfer function, point spread function, and Strehl ratio were calculated. RESULTS: At 3 mm pupil, no statistically significant differences were found between both incision sizes for any implantable collamer lens power, except for -15 diopter (D) implantable collamer lens at 25 cycles/degree (cpd) (P < .05). At 5 mm pupil, statistically significant differences in Strehl ratio, VA, and contrast sensitivity were found between both incision sizes for all implantable collamer lens powers (P < .05). The outcomes were better with small incision. Implantable collamer lens power also affected the optical and visual quality. At 3 mm pupil, no statistically significant differences were found in VA and contrast sensitivity between implantable collamer lens powers, except between -3 and -15 D at low-contrast VA and at 2,0 and 25 cpd (P < .05). At 5 mm pupil, no statistically significant differences were found in Strehl ratio, VA, and contrast sensitivity between -3 and -6 D implantable collamer lens, but they did become apparent for -15 D implantable collamer lens for both incision sizes, all contrasts and spatial frequencies (P < .05). CONCLUSIONS: The implantable collamer lens provides good optical and visual quality, although these outcomes decreased with large-incision surgery because of the increase of aberrations. (Am J Ophthalmol 2013;155:499-507. (C) 2013 by Elsevier Inc. All rights reserved.)