Red Blood Cell-Derived Nitric Oxide Bioactivity and Hypoxic Vasodilation To β93 or not to β93?

被引：12
作者：
Schmidt, Harald H. H. W. [1 ]
Feelisch, Martin [2 ]
机构：
[1] Maastricht Univ, Fac Hlth Med & Life Sci, Dept Pharmacol & Personalised Med, NL-6200 MD Maastricht, Netherlands
[2] Univ Southampton, Southampton Gen Hosp, Fac Med, Clin & Expt Sci, Southampton, Hants, England
来源：
CIRCULATION | 2019年 / 139卷 / 23期
基金：
英国医学研究理事会; 欧盟地平线“2020”; 英国惠康基金; 欧洲研究理事会;
关键词：
Editorials; erythrocytes; hypoxia; nitric oxide; vasodilation; S-NITROSOHEMOGLOBIN; HEMOGLOBIN;
D O I：
10.1161/CIRCULATIONAHA.119.040423
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：2664 / 2667
页数：4
相关论文
共 15 条
[1]   Human red blood cells at work: identification and visualization of erythrocytic eNOS activity in health and disease [J].
Cortese-Krott, Miriam M. ;
Rodriguez-Mateos, Ana ;
Sansone, Roberto ;
Kuhnle, Gunter G. C. ;
Thasian-Sivarajah, Sivatharsini ;
Krenz, Thomas ;
Horn, Patrick ;
Krisp, Christoph ;
Wolters, Dirk ;
Heiss, Christian ;
Kroencke, Klaus-Dietrich ;
Hogg, Neil ;
Feelisch, Martin ;
Kelm, Malte .
BLOOD, 2012, 120 (20) :4229-4237
[2]   Augmented skeletal muscle hyperaemia during hypoxic exercise in humans is blunted by combined inhibition of nitric oxide and vasodilating prostaglandins [J].
Crecelius, Anne R. ;
Kirby, Brett S. ;
Voyles, Wyatt F. ;
Dinenno, Frank A. .
JOURNAL OF PHYSIOLOGY-LONDON, 2011, 589 (14) :3671-3683
[3]   Skeletal muscle vasodilation during systemic hypoxia in humans [J].
Dinenno, Frank A. .
JOURNAL OF APPLIED PHYSIOLOGY, 2016, 120 (02) :216-225
[4]   Enhanced nitric oxide production is a universal response to hypoxic stress [J].
Feelisch, Martin .
NATIONAL SCIENCE REVIEW, 2018, 5 (04) :532-533
[5]   Nitric oxide's reactions with hemoglobin: a view through the SNO-storm [J].
Gladwin, MT ;
Lancaster, JR ;
Freeman, BA ;
Schechter, AN .
NATURE MEDICINE, 2003, 9 (05) :496-500
[6]   S-nitrosohaemoglobin: A dynamic activity of blood involved in vascular control [J].
Jia, L ;
Bonaventura, C ;
Bonaventura, J ;
Stamler, JS .
NATURE, 1996, 380 (6571) :221-226
[7]   Subunit Disassembly Pathway of Human Hemoglobin Revealing the Site-Specific Role of Its Cysteine Residues [J].
Kan, Heng-I ;
Chen, I-Ying ;
Zulfajri, Muhammad ;
Wang, Chia C. .
JOURNAL OF PHYSICAL CHEMISTRY B, 2013, 117 (34) :9831-9839
[8]   Cell-free and erythrocytic S-nitrosohemoglobin inhibits human platelet aggregation [J].
Pawloski, JR ;
Swaminathan, RV ;
Stamler, JS .
CIRCULATION, 1998, 97 (03) :263-267
[9]   Blood flow regulation by S-nitrosohemoglobin in the physiological oxygen gradient [J].
Stamler, JS ;
Jia, L ;
Eu, JP ;
McMahon, TJ ;
Demchenko, IT ;
Bonaventura, J ;
Gernert, K ;
Piantadosi, CA .
SCIENCE, 1997, 276 (5321) :2034-2037
[10]   Hemoglobin β93 Cysteine Is Not Required for Export of Nitric Oxide Bioactivity From the Red Blood Cell [J].
Sun, Chiao-Wang ;
Yang, Jiangning ;
Kleschyov, Andrei L. ;
Zhuge, Zhengbing ;
Carlstrom, Mattias ;
Pernow, John ;
Wajih, Nadeem ;
Isbell, T. Scott ;
Oh, Joo-Yeun ;
Cabrales, Pedro ;
Tsai, Amy G. ;
Townes, Tim ;
Kim-Shapiro, Daniel B. ;
Patel, Rakesh P. ;
Lundberg, Jon O. .
CIRCULATION, 2019, 139 (23) :2654-2663
12