MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status (vol 124, pg 547, 2012)

被引:2
作者
Bady, Pierre [1 ,2 ,3 ]
Sciuscio, Davide [1 ]
Diserens, Annie-Claire [1 ]
Bloch, Jocelyne [1 ]
van den Bent, Martin J. [4 ]
Marosi, Christine [5 ]
Dietrich, Pierre-Yves [6 ]
Weller, Michael [7 ,8 ]
Mariani, Luigi [9 ]
Heppner, Frank L. [10 ]
Macdonald, David R. [11 ]
Lacombe, Denis [12 ]
Stupp, Roger [1 ]
Delorenzi, Mauro [2 ,3 ,13 ]
Hegi, Monika E. [1 ,14 ]
机构
[1] Univ Lausanne Hosp, Dept Clin Neurosci, Lausanne, Switzerland
[2] Swiss Inst Bioinformat, Bioinformat Core Facil, Lausanne, Switzerland
[3] Univ Lausanne Hosp, Dept Format & Rech, Lausanne, Switzerland
[4] Erasmus MC, Dept Neurol, Rotterdam, Netherlands
[5] Med Univ Vienna, Vienna, Austria
[6] Univ Hosp Geneva, Geneva, Switzerland
[7] Univ Tubingen, Dept Neurol, Tubingen, Germany
[8] Univ Zurich Hosp, Dept Neurol, CH-8091 Zurich, Switzerland
[9] Inselspital Bern, Dept Neurosurg, CH-3010 Bern, Switzerland
[10] Univ Zurich Hosp, Dept Neuropathol, CH-8091 Zurich, Switzerland
[11] Univ Western Ontario, London Reg Canc Program, London Hlth Sci Ctr, London, ON, Canada
[12] EORTC Headquaters, Brussels, Belgium
[13] ISREC SV EPFL, Natl Ctr Competence Res Mol Oncol, Lausanne, Switzerland
[14] Ctr Hosp Univ Vaudois CHUV BH19 110, Dept Neurosurg, Lab Brain Tumor Biol & Genet, CH-1011 Lausanne, Switzerland
关键词
D O I
10.1007/s00401-013-1134-5
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
引用
收藏
页码:159 / 159
页数:1
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[1]   MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status [J].
Bady, Pierre ;
Sciuscio, Davide ;
Diserens, Annie-Claire ;
Bloch, Jocelyne ;
van den Bent, Martin J. ;
Marosi, Christine ;
Dietrich, Pierre-Yves ;
Weller, Michael ;
Mariani, Luigi ;
Heppner, Frank L. ;
Mcdonald, David R. ;
Lacombe, Denis ;
Stupp, Roger ;
Delorenzi, Mauro ;
Hegi, Monika E. .
ACTA NEUROPATHOLOGICA, 2012, 124 (04) :547-560