Hydrotalcite: recyclable, novel heterogeneous catalyst for facile, environmentally benign and high yielding multi-component synthesis and mechanistic study under solvent free conditions

被引：38

作者：

Sahu, Pramod Kumar ^{[1
,2
]}

Sahu, Praveen Kumar ^{[2
,3
]}

Jain, Raginee ^{[2
]}

Yadav, Ramjilal ^{[1
]}

Agarwal, Dau Dayal ^{[1
,2
,3
]}

机构：

[1] Jiwaji Univ, Sch Studies Chem, Gwalior 474011, Madhya Pradesh, India

[2] Jiwaji Univ, Dept Ind Chem, Gwalior 474011, Madhya Pradesh, India

[3] Jagdishprasad Jhabarmal Tibrewala Univ, Chudela 333001, Rajasthan, India

来源：

CATALYSIS SCIENCE & TECHNOLOGY | 2012年 / 2卷 / 12期

关键词：

ONE-POT SYNTHESIS; CYCLIZATION REACTIONS; POLYTYPE DIVERSITY; FINE CHEMICALS; IONIC LIQUIDS; CONDENSATION; DERIVATIVES; 3-COMPONENT; ANTIBACTERIAL; TOXICITY;

D O I：

10.1039/c2cy20067h

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The synthesis of the 4H-pyrimido[2,1-b][1,3] benzothiazole (1a-1h), 1,2,4-triazoloquinazolines (2a,2b), octahydroquinazolinones (3a,3b) and fused thiazolo[2,3-b] quinazolinone (4a,4b) by multicomponent reactions using aldehydes, dicarbonyl and 2-amino benzothiazole/3-amino-1,2,4-triazole/urea/thiorea has been carried out in the presence of Mg-Al-CO3 and Ca-Al-CO3 hydrotalcite as a heterogeneous catalyst. Hydrotalcites need short reaction times, are non-toxic, easy to work up and reusable under solvent free conditions, hence making this process environment friendly. A detailed mechanistic study shows that the reaction using urea proceeds through imine intermediate 6. In addition, we have isolated and characterized the key intermediate of the reaction by using hydrotalcite.

引用

页码：2465 / 2475

页数：11

共 41 条

[21] A Green Synthesis of 3, 4-Dihydropyrimidin-2(1H)-ones via One-Pot Multi-Component Reaction by Using Cuttlebone as a Natural Catalyst under Solvent-Free Conditions [J].

Firoozeh, Nooshin ;

Rezazadeh, Soodabeh ;

Izanloo, Cobra .

JOURNAL OF THE MEXICAN CHEMICAL SOCIETY, 2017, 61 (03) :241-249

[22] Ag-TiO2 Nanocomposite: An Efficient Heterogeneous and Reusable Catalyst for the Three-Component Synthesis of 1-Amidoalkyl-2-naphthols under Solvent-Free Conditions [J].

Firozi, S. ;

Vahdat, S. M. ;

Khaksar, S. ;

Hatami, M. .

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2024, 60 (01) :131-137

[23] RETRACTED: Introduction of a trinuclear manganese(iii) catalyst on the surface of magnetic cellulose as an eco-benign, efficient and reusable novel heterogeneous catalyst for the multi-component synthesis of new derivatives of xanthene (Retracted Article) [J].

Kargar, Pouya Ghamari ;

Bagherzade, Ghodsieh ;

Eshghi, Hossein .

RSC ADVANCES, 2021, 11 (08) :4339-4355

[24] An Efficient, Green, and Solvent-free Multi-component Synthesis of Benzimidazolo/Benzothiazolo Quinazolinone Derivatives Using Sc (OTf)3 Catalyst Under Controlled Microwave Irradiation [J].

Gajaganti, Somaiah ;

Kumari, Savita ;

Kumar, Dhirendra ;

Allam, Bharat Kumar ;

Srivastava, Vandana ;

Singh, Sundaram .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 2018, 55 (11) :2578-2584

[25] Silica Gel-Supported Polyphosphoric Acid (PPA/SiO2): An Efficient and Reusable Heterogeneous Catalyst for Facile Synthesis of 14-Aryl-14H-dibenzo[a,j]xanthenes under Solvent-free Conditions [J].

Khojastehnezhad, Amir ;

Davoodnia, Abolghasem ;

Bakavoli, Mehdi ;

Tavakoli-Hoseini, Niloofar ;

Zeinali-Dastmalbaf, Mohsen .

CHINESE JOURNAL OF CHEMISTRY, 2011, 29 (02) :297-302

[26] SYNTHESIS OF 1-AMIDOALKYL-2-NAPHTHOLS BASED ON A THREE-COMPONENT REACTION CATALYZED BY BORIC ACID AS A SOLID HETEROGENEOUS CATALYST UNDER SOLVENT-FREE CONDITIONS [J].

Karimi-Jaberi, Zahed ;

Fakhraei, Hadi .

BULLETIN OF THE CHEMICAL SOCIETY OF ETHIOPIA, 2012, 26 (03) :473-478

[27] Silica functionalized sulphonic acid coated with ionic liquid: an efficient and recyclable heterogeneous catalyst for the one-pot synthesis of 1,4-dihydropyridines under solvent-free conditions [J].

Sharma, Pankaj ;

Gupta, Monika .

GREEN CHEMISTRY, 2015, 17 (02) :1100-1106

[28] Glycerol: A Promising Benign Solvent for Catalyst Free One-Pot Multi-Component Synthesis of Pyrano[2,3-c]pyrazoles and Tetrahydro-benzo[b]pyrans at Ambient Temperature [J].

Hamid, Afaf Abdel ;

Abd-Elmonem, Mohamed ;

Hayallah, Alaa M. ;

Elsoud, Fatma A. Abo ;

Sadek, Kamal U. .

CHEMISTRYSELECT, 2017, 2 (33) :10689-10693

[29] Synthesis of 1,8-dioxo-octahydroxanthenes utilizing nanodiatomite@melamine-SO3H as a novel heterogeneous catalyst under solvent-free conditions [J].

Davoodi, Elham ;

Tahanpesar, Elham ;

Massah, Ahmad Reza .

JOURNAL OF CHEMICAL SCIENCES, 2022, 134 (03)

[30] Magnetic Co-doped NiFe2O4 Nanocomposite: A Heterogeneous and Recyclable Catalyst for the One-Pot Synthesis of Benzimidazoles, Benzoxazoles and Benzothiazoles under Solvent-Free Conditions [J].

Karimian, Azam ;

Kakhki, Roya Mohammadzadeh ;

Beidokhti, Hamideh Kargar .

JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 2017, 64 (11) :1316-1325

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