Clinical Applications of The Cancer Genome Atlas Project (TCGA) for Squamous Cell Lung Carcinoma

被引:0
|
作者
Devarakonda, Siddhartha [1 ]
Morgensztern, Daniel [2 ]
Govindan, Ramaswamy [2 ]
机构
[1] St Lukes Hosp, Dept Internal Med, Chesterfield, MO USA
[2] Washington Univ, Sch Med, Div Med Oncol, St Louis, MO USA
来源
ONCOLOGY-NEW YORK | 2013年 / 27卷 / 09期
关键词
FACTOR RECEPTOR MUTATIONS; TRANSCRIPTION FACTOR NRF2; PHASE-II; 1ST-LINE TREATMENT; CHEMONAIVE PATIENTS; 3Q AMPLIFICATION; 3RD-LINE THERAPY; STEM-CELLS; OPEN-LABEL; GROWTH;
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Very little progress has been made in the treatment of patients with metastatic squamous cell lung cancer over the past 2 decades. Identification of novel molecular alterations for targeted therapies is necessary to improve outcomes. Advances in genomic technology have now made it possible to analyze the genomic landscape of tumor tissues comprehensively. We summarize here key findings from the comprehensive analysis of squamous cell lung cancer by The Cancer Genome Atlas group and discuss the clinical implications of these findings.
引用
收藏
页码:899 / 906
页数:8
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