Clinical Applications of The Cancer Genome Atlas Project (TCGA) for Squamous Cell Lung Carcinoma

被引：0

作者：

Devarakonda, Siddhartha ^{[1
]}

Morgensztern, Daniel ^{[2
]}

Govindan, Ramaswamy ^{[2
]}

机构：

[1] St Lukes Hosp, Dept Internal Med, Chesterfield, MO USA

[2] Washington Univ, Sch Med, Div Med Oncol, St Louis, MO USA

来源：

ONCOLOGY-NEW YORK | 2013年 / 27卷 / 09期

关键词：

FACTOR RECEPTOR MUTATIONS; TRANSCRIPTION FACTOR NRF2; PHASE-II; 1ST-LINE TREATMENT; CHEMONAIVE PATIENTS; 3Q AMPLIFICATION; 3RD-LINE THERAPY; STEM-CELLS; OPEN-LABEL; GROWTH;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Very little progress has been made in the treatment of patients with metastatic squamous cell lung cancer over the past 2 decades. Identification of novel molecular alterations for targeted therapies is necessary to improve outcomes. Advances in genomic technology have now made it possible to analyze the genomic landscape of tumor tissues comprehensively. We summarize here key findings from the comprehensive analysis of squamous cell lung cancer by The Cancer Genome Atlas group and discuss the clinical implications of these findings.

引用

页码：899 / 906

页数：8

共 50 条

[1] Molecular Histologic Correlations in the Cancer Genome Atlas (TCGA) Study of Lung Squamous Cell Carcinoma (SQC)
Travis, W. D.
Rekhtman, N.
Shen, R.
Yi, E. S.
Aubry, M. C.
Cheney, R.
Dacic, S.
Flieder, D.
Funkhouser, W.
Illei, P.
Myers, J.
Tsao, M. S.
Wilkerson, M.
Hammerman, P.
Govindan, R.
Hayes, N.
Meyerson, M.
MODERN PATHOLOGY, 2012, 25 : 491A - 491A
[2] Molecular Histologic Correlations in the Cancer Genome Atlas (TCGA) Study of Lung Squamous Cell Carcinoma (SQC)
Travis, W. D.
Reklaman, N.
Shen, R.
Yi, E. S.
Aubry, M. C.
Cheney, R.
Dacic, S.
Flieder, D.
Funkhouser, W.
Illei, P.
Myers, J.
Tsao, M. S.
Wilkerson, M.
Hammerman, P.
Govindan, R.
Hayes, N.
Meyerson, M.
LABORATORY INVESTIGATION, 2012, 92 : 491A - 491A
[3] The clinical applications of The Cancer Genome Atlas project for bladder cancer
Creighton, Chad J.
EXPERT REVIEW OF ANTICANCER THERAPY, 2018, 18 (10) : 973 - 980
[4] Development of the pre-cancer genome atlas (PCGA) for squamous cell lung carcinoma
Beane, Jennifer E.
Campbell, Joshua
Moy, Christopher
Perdomo, Catalina
Schaffer, Michael
Mazzilli, Sarah
Geshalter, Yaron
Kantrowitz, Jacob
Zhang, Liye
Jenkins, David
Pine, Mary Beth
Dhillon, Samjot
Liu, Gang
Liu, Hanqiao
Zhang, Sherry
Vick, Jessica
Monti, Stefano
Johnson, Evan
Platero, Suso
Lenburg, Marc
Reid, Mary
Spira, Avrum
CANCER RESEARCH, 2015, 75
[5] Identification of microRNAs as novel biomarkers for esophageal squamous cell carcinoma: a study based on The Cancer Genome Atlas (TCGA) and bioinformatics
Li Cheng-Yun
Zhang Wen-Wen
Xiang Ji-Lian
Wang Xing-Hua
Li Jin
Wang Jun-Ling
中华医学杂志英文版, 2019, 132 (18) : 2213 - 2222
[6] Identification of microRNAs as novel biomarkers for esophageal squamous cell carcinoma: a study based on The Cancer Genome Atlas (TCGA) and bioinformatics
Li, Cheng-Yun
Zhang, Wen-Wen
Xiang, Ji-Lian
Wang, Xing-Hua
Li, Jin
Wang, Jun-Ling
CHINESE MEDICAL JOURNAL, 2019, 132 (18) : 2213 - 2222
[7] Molecular characteristics of non-small cell lung cancer with reduced CHFR expression in The Cancer Genome Atlas (TCGA) project
Brodie, Seth A.
Li, Ge
Brandes, Johann C.
RESPIRATORY MEDICINE, 2015, 109 (01) : 131 - 136
[8] The Cancer Genome Atlas (TCGA) project on endometrial carcinoma: Initial data and preliminary genomic analysis
Levine, D.
Mardis, E.
GYNECOLOGIC ONCOLOGY, 2012, 125 (03) : 772 - 772
[9] A pan-cancer proteomic analysis of The Cancer Genome Atlas (TCGA) project
Akbani, Rehan
Ng, Kwok-Shing
Werner, Henrica M.
Zhang, Fan
Ju, Zhenlin
Liu, Wenbin
Yang, Ji-Yeon
Lu, Yiling
Weinstein, John N.
Mills, Gordon B.
CANCER RESEARCH, 2014, 74 (19)
[10] Integrated molecular characterization of uterine carcinosarcoma in The Cancer Genome Atlas (TCGA) project
Akbani, Rehan
Levine, Douglas A.
CANCER RESEARCH, 2016, 76

← 1 2 3 4 5 →