Background: Mitral annular calcification (MAC) is associated with several cardiovascular disorders including coronary artery disease (CAD), atrial fibrillation, heart failure, ischemic stroke and increased mortality. Epicardial fat thickness (EFT) has strong correlation with obesity, CAD, insulin resistance, metabolic syndrome, hypertension, diabetes mellitus, and atherosclerosis. There are strong similarities between EFT and MAC from the aspect of risk factors and pathogenesis. Objective: In this study we aimed to investigate the EFT in patients with MAC. Methods: The study group consisted of 78 patients with MAC. An age, gender and body mass index matched control group consisted of 47 subjects who admitted to echocardiography laboratory due to suspicion of organic heart disease and eventually found to be free of MAC. We measured EFT in patients with MAC and control subjects. Results: EFT was significantly higher in patients with MAC than in control subjects (5.7 +/- 0.9 vs. 4.4 +/- 0.6 mm respectively; P<0.001). Correlation analysis indicated that EFT was positively correlated with presence of MAC (p<0.001, r=0.597). Conclusion: We showed that EFT was significantly elevated in patients with MAC and it was positively correlated with MAC.
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Massachusetts Gen Hosp, Dept Med, Div Gen Med, Boston, MA 02114 USA
Harvard Univ, Sch Med, Boston, MA USA
Seoul Natl Univ, Coll Med, Bundang Hosp, Dept Internal Med, Songnam 463707, South KoreaMassachusetts Gen Hosp, Dept Med, Div Gen Med, Boston, MA 02114 USA
Lim, Soo
;
Meigs, James B.
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Massachusetts Gen Hosp, Dept Med, Div Gen Med, Boston, MA 02114 USA
Harvard Univ, Sch Med, Boston, MA USAMassachusetts Gen Hosp, Dept Med, Div Gen Med, Boston, MA 02114 USA
机构:
Univ Naples Federico II, Dipartimento Sci Med Traslaz, I-80131 Naples, Italy
IRCCS, Inst Telese, Salvatore Maugeri Fdn, Telese, BN, ItalyUniv Naples Federico II, Dipartimento Sci Med Traslaz, I-80131 Naples, Italy
Rengo, Giuseppe
;
Pagano, Gennaro
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Univ Naples Federico II, Dipartimento Sci Med Traslaz, I-80131 Naples, ItalyUniv Naples Federico II, Dipartimento Sci Med Traslaz, I-80131 Naples, Italy
Pagano, Gennaro
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D'Esposito, Vittoria
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Passaretti, Federica
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Univ Naples Federico II, Dipartimento Sci Med Traslaz, I-80131 Naples, ItalyUniv Naples Federico II, Dipartimento Sci Med Traslaz, I-80131 Naples, Italy
Passaretti, Federica
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Caruso, Aurelio
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Casa Cura San Michele, Maddaloni, CE, ItalyUniv Naples Federico II, Dipartimento Sci Med Traslaz, I-80131 Naples, Italy
Caruso, Aurelio
;
Grimaldi, Maria Gabriella
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Casa Cura San Michele, Maddaloni, CE, ItalyUniv Naples Federico II, Dipartimento Sci Med Traslaz, I-80131 Naples, Italy
Grimaldi, Maria Gabriella
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Lonobile, Tommaso
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Casa Cura San Michele, Maddaloni, CE, ItalyUniv Naples Federico II, Dipartimento Sci Med Traslaz, I-80131 Naples, Italy
Lonobile, Tommaso
;
Baldascino, Francesco
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Casa Cura San Michele, Maddaloni, CE, ItalyUniv Naples Federico II, Dipartimento Sci Med Traslaz, I-80131 Naples, Italy
Baldascino, Francesco
;
De Bellis, Antonio
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Casa Cura San Michele, Maddaloni, CE, ItalyUniv Naples Federico II, Dipartimento Sci Med Traslaz, I-80131 Naples, Italy
De Bellis, Antonio
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Formisano, Pietro
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Ferrara, Nicola
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Univ Naples Federico II, Dipartimento Sci Med Traslaz, I-80131 Naples, ItalyUniv Naples Federico II, Dipartimento Sci Med Traslaz, I-80131 Naples, Italy
机构:
Massachusetts Gen Hosp, Dept Med, Div Gen Med, Boston, MA 02114 USA
Harvard Univ, Sch Med, Boston, MA USA
Seoul Natl Univ, Coll Med, Bundang Hosp, Dept Internal Med, Songnam 463707, South KoreaMassachusetts Gen Hosp, Dept Med, Div Gen Med, Boston, MA 02114 USA
Lim, Soo
;
Meigs, James B.
论文数: 0引用数: 0
h-index: 0
机构:
Massachusetts Gen Hosp, Dept Med, Div Gen Med, Boston, MA 02114 USA
Harvard Univ, Sch Med, Boston, MA USAMassachusetts Gen Hosp, Dept Med, Div Gen Med, Boston, MA 02114 USA
机构:
Univ Naples Federico II, Dipartimento Sci Med Traslaz, I-80131 Naples, Italy
IRCCS, Inst Telese, Salvatore Maugeri Fdn, Telese, BN, ItalyUniv Naples Federico II, Dipartimento Sci Med Traslaz, I-80131 Naples, Italy
Rengo, Giuseppe
;
Pagano, Gennaro
论文数: 0引用数: 0
h-index: 0
机构:
Univ Naples Federico II, Dipartimento Sci Med Traslaz, I-80131 Naples, ItalyUniv Naples Federico II, Dipartimento Sci Med Traslaz, I-80131 Naples, Italy
Pagano, Gennaro
;
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D'Esposito, Vittoria
;
Passaretti, Federica
论文数: 0引用数: 0
h-index: 0
机构:
Univ Naples Federico II, Dipartimento Sci Med Traslaz, I-80131 Naples, ItalyUniv Naples Federico II, Dipartimento Sci Med Traslaz, I-80131 Naples, Italy
Passaretti, Federica
;
Caruso, Aurelio
论文数: 0引用数: 0
h-index: 0
机构:
Casa Cura San Michele, Maddaloni, CE, ItalyUniv Naples Federico II, Dipartimento Sci Med Traslaz, I-80131 Naples, Italy
Caruso, Aurelio
;
Grimaldi, Maria Gabriella
论文数: 0引用数: 0
h-index: 0
机构:
Casa Cura San Michele, Maddaloni, CE, ItalyUniv Naples Federico II, Dipartimento Sci Med Traslaz, I-80131 Naples, Italy
Grimaldi, Maria Gabriella
;
Lonobile, Tommaso
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h-index: 0
机构:
Casa Cura San Michele, Maddaloni, CE, ItalyUniv Naples Federico II, Dipartimento Sci Med Traslaz, I-80131 Naples, Italy
Lonobile, Tommaso
;
Baldascino, Francesco
论文数: 0引用数: 0
h-index: 0
机构:
Casa Cura San Michele, Maddaloni, CE, ItalyUniv Naples Federico II, Dipartimento Sci Med Traslaz, I-80131 Naples, Italy
Baldascino, Francesco
;
De Bellis, Antonio
论文数: 0引用数: 0
h-index: 0
机构:
Casa Cura San Michele, Maddaloni, CE, ItalyUniv Naples Federico II, Dipartimento Sci Med Traslaz, I-80131 Naples, Italy
De Bellis, Antonio
;
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Formisano, Pietro
;
Ferrara, Nicola
论文数: 0引用数: 0
h-index: 0
机构:
Univ Naples Federico II, Dipartimento Sci Med Traslaz, I-80131 Naples, ItalyUniv Naples Federico II, Dipartimento Sci Med Traslaz, I-80131 Naples, Italy