Bioactivity of extracts of Musa paradisiaca L. obtained with compressed propane and supercritical CO2

被引：21

作者：

Correa, Madeline ^{[1
]}

Bombardelli, Michele C. M. ^{[2
]}

Fontana, Pamela Dias ^{[4
]}

Bovo, Fernanda ^{[3
,4
]}

Messias-Reason, Iara Jose ^{[4
]}

Baron Maurer, Juliana Bello ^{[3
]}

Corazza, Marcos Lucio ^{[1
]}

机构：

[1] Univ Fed Parana, Dept Chem Engn, BR-81531990 Curitiba, Parana, Brazil

[2] State Univ Midwest, Dept Food Engn, BR-85040080 Guarapuava, PR, Brazil

[3] Univ Fed Parana, Dept Biochem & Mol Biol, NUPPLAMED, POB 19046, BR-81531900 Curitiba, Parana, Brazil

[4] Univ Fed Parana, Dept Med Pathol, BR-80060900 Curitiba, Parana, Brazil

来源：

JOURNAL OF SUPERCRITICAL FLUIDS | 2017年 / 122卷

关键词：

Antioxidant activity; Antibacterial activity; Anti-complement activity; Anti-inflammatory; Banana; GINGER ZINGIBER-OFFICINALE; ANTIOXIDANT ACTIVITY; CARBON-DIOXIDE; CHEMICAL-COMPOSITION; FLUID EXTRACTION; OIL; ANTIBACTERIAL; PERSPECTIVES; ECULIZUMAB; CAPACITY;

D O I：

10.1016/j.supflu.2016.12.004

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

This paper reports the assessment of bioactivity of inflorescences extracts of Musa paradisiaca L. obtained using supercritical CO2 (scCO(2)) and compressed propane as solvents. The effects of extraction conditions over the antioxidant and antibacterial activity were evaluated. The highest antioxidant activity (3576.86 +/- 18.36 mg of a-tocopherol/g extract) was found for extracts obtained using scCO(2) as solvent at 353.15 K and 25.0 MPa. The extracts did not showed inhibitionfor the bacteria tested. The immunomodulatory effects of the extracts obtained by the extraction with 308.15 K and 3.0 MPa showed a significant inhibitory effect on the alternative pathway (AP) in all concentrations tested (333-5.2 mu g mL(-1)), with at least 70% reduction in the AP-induced haemolysis when compared with the 100% haemolysis control without the use of the extract. (C) 2016 Elsevier B.V. All rights reserved.

引用

页码：63 / 69

页数：7

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