On-chip laser Doppler vibrometer for arterial pulse wave velocity measurement

被引：41

作者：

Li, Yanlu ^{[1
,2
]}

Segers, Patrick ^{[3
]}

Dirckx, Joris ^{[4
]}

Baets, Roel ^{[1
,2
]}

机构：

[1] Ghent Univ IMEC, INTEC Dept, Photon Res Grp, B-9000 Ghent, Belgium

[2] Univ Ghent, Ctr Nano & Biophoton NB Photon, B-9000 Ghent, Belgium

[3] Univ Ghent, IBiTech bioMMeda, B-9000 Ghent, Belgium

[4] Univ Antwerp, Lab Biomed Phys, B-2020 Antwerp, Belgium

来源：

BIOMEDICAL OPTICS EXPRESS | 2013年 / 4卷 / 07期

关键词：

CAROTID-ARTERY; INSULATOR;

D O I：

10.1364/BOE.4.001229

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Pulse wave velocity (PWV) is an important marker for cardiovascular risk. The Laser Doppler vibrometry has been suggested as a potential technique to measure the local carotid PWV by measuring the transit time of the pulse wave between two locations along the common carotid artery (CCA) from skin surface vibrations. However, the present LDV setups are still bulky and difficult to handle. We present in this paper a more compact LDV system integrated on a CMOS-compatible silicon-on-insulator substrate. In this system, a chip with two homodyne LDVs is utilized to simultaneously measure the pulse wave at two different locations along the CCA. Measurement results show that the dual-LDV chip can successfully conduct the PWV measurement. (C) 2013 Optical Society of America

引用

收藏

页码：1229 / 1235

页数：7

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