A three component one-pot procedure for the synthesis of [1,2,4]triazolo/benzimidazolo-quinazolinone derivatives in the presence of H6P2W18O62 • 18H2O as a green and reusable catalyst

被引：111

作者：

Heravi, Majid M. ^{[1
]}

Ranjbar, Leila ^{[1
]}

Derikvand, Fatemeh ^{[1
]}

Alimadadi, Behnoush ^{[1
]}

Oskooie, Hossien A. ^{[1
]}

Bamoharram, Fatemeh F. ^{[2
]}

机构：

[1] Alzahra Univ, Sch Sci, Dept Chem, Tehran, Iran

[2] Islamic Azad Univ, Dept Chem, Mashhad Branch, Mashhad, Iran

来源：

MOLECULAR DIVERSITY | 2008年 / 12卷 / 3-4期

关键词：

Quinazolinones; 2-Aminobenzimidazole; 3-Amino-1,2,4-triazole; Heteropolyacids; Reusable catalysts;

D O I：

10.1007/s11030-008-9086-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A rapid and efficient one-pot method for the synthesis of quinazolinone derivatives and related heterocycles by condensation of 2-amino benzimidazole and 3-amino-1,2,4-triazole, as amine sources, with dimedone and different aldehydes in the presence of H6P2W18O62 center dot 18H(2)O as a green and reusable catalyst in refluxing acetonitrile has been developed.

引用

页码：181 / 185

页数：5

共 28 条

[1] Synthesis and pharmacological investigation of novel 4-benzyl-1-substituted-4H-[1,2,4]triazolo[4,3-a]quinazolin-5-ones as new class of H1-antihistaminic agents [J].